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Digitale Medien

Autoradiographic assessment of 3H-proline uptake by osteoblasts following guanethidine-induced sympathectomy in the rat (1981)

Singh, I. J. ; Klein, R. M. ; Herskovits, M.

Springer

Cell & tissue research 216 (1981), S. 215-220

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ISSN: 1432-0878

Schlagwort(e): Autoradiography ; 3H-proline ; Osteoblasts ; Sympathectomy ; Guanethidine-sulfate

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary Sympathectomy was carried out in rats by injections of guanethidine-sulfate from birth to 14 days of age. At 45 days of age, the activity of osteoblastic cells was monitored by 3H-proline autoradiography. Effectiveness of sympathectomy was verified by light-microscopic examination of superior cervical and celiac ganglia. Grain counts over periosteal osteoblasts of the femoral diaphysis and osteoblasts mesial to the first molar in the mandible demonstrated a significantly reduced uptake of 3H-proline in the sympathectomized rats. The data provide direct evidence of sympathetic influence on osteoblastic activity and suggest that sympathectomy may result in the loss of a trophic influence which is important in the regulation of osteogenesis.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00234556

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Digitale Medien

Generalized Rouse-Zimm theory for polymer solutions (1981)

Hess, W. ; Jilge, W. ; Klein, R.

New York : Wiley-Blackwell

Journal of Polymer Science: Polymer Physics Edition 19 (1981), S. 849-862

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Details

ISSN: 0098-1273

Schlagwort(e): Physics ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie , Physik

Notizen: Generalized Rouse-Zimm equations are derived using a local equilibrium ansatz for the segment distribution function. The relaxation frequencies depend on excluded-volume effects and other interactions such as entanglement in semidilute solutions through exact static correlation functions. For the case of ring polymers general expressions are given for diffusion coefficients and mean-square displacements. By use of the “blob” model, explicit results are presented for a dilute good-solvent system.

Zusätzliches Material: 2 Ill.