ISSN:
0006-3592
Keywords:
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
Growth of Aspergillus parasiticus and accumulation of aflatoxin B1 in the medium that contained antifungal agents were monitored during the growth cycle of the mold. The antifungal agents tested are the food additive (antioxidant), butylated hydroxyanisole (BHA), the pesticide, isoprothiolane, and the antibiotic, nystatin. Growth of the mold was quantified using a newly developed criterion, named the growth coefficient (GC). The GC values were calculated from the growth parameters of the logistic function that fits the growth curve of the mold. At the range of concentrations of additives studied, maxima of growth inhibition were 31.3, 23.1, and 43.6% at 60 ppm of BHA, 70 ppm of isoprothiolane, and 45 units of nystatin/mL, respectively. The ability of the mold to accumulate aflatoxin B1 in its medium [as measured by the accumulation rate constant (α)] In the presence of various levels of the antifungal agents was concentration-dependent. Sixty parts per million of BHA decreased the value of α by 71.7%, 30 units of nystatin/mL was the most effective concentration of that antibiotic and resulted in only 23.5% inhibition, and isoprothiolane at all its levels stimulated elaboration of aflatoxin B1 by the mold.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bit.260260103
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