ISSN:
1432-0533
Keywords:
Membrane specialization
;
Globoid cell
;
Astrocyte
;
Globoid cell leukodystrophy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Subplasmalemmal linear densities (Yajima et al. 1977 a) were the membrane specializations observed in globoid cells in globoid cell leukodystrophy (GLD) and in the cells of the mononuclear phagocytic system (Kawanami et al. 1980). In the spinal cord of the twitcher mouse, an authentic murine model of GLD, somewhat similar membrane specializations were noted in astrocytes, and on some occasions, a spot desmosome-like cellular contact was observed between globoid cells, which were likely to be mesodermal in origin, and astrocytes, which are of ectodermal origin. Possible significance of such apparent cellular contact is discussed briefly.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00688603
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