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  • 1980-1984  (2)
  • Analytical Chemistry and Spectroscopy  (1)
  • Heart: malformations  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 393 (1981), S. 61-73 
    ISSN: 1432-2307
    Keywords: Atrial septum ; Central fibrous body ; Heart: development ; Heart: fibrous skeleton ; Heart: malformations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The fibrous skeleton of the human heart is composed of several parts which are formed from different, mainly extracardiac sources. The atrioventricular valve rings are formed by invagination of sulcus tissue at the atrioventricular and bulboventricular transitions. The atrial part of the central fibrous body is formed from an ingrowth of tissue from the dorsal mesocardium, the ventricular part from ingrowth of sulcus tissue towards an endocardial structure, the left bulbar ridge. During valve development the atrioventricular endocardial cushions, initially situated between the developing atrial and ventricular parts of the central fibrous body, are almost completely removed downwards into the ventricular cavities. However, a small portion of these cushions remains on top of the ventricular septum, is “trapped” by the surrounding sulcus tissues and becomes incorporated in the central fibrous body. These embryological findings on this centrally located area of the heart have implications for certain types of cardiac abnormalities. In this respect the atrioventricular conduction system, cor triatriatum sinistrum and atrioventricular defect are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 22 (1984), S. 539-542 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The synthesis of optically active (1R,2R)- and (1S,2R)-2-deuterio-2,3-dihydro-2-methyl-6-nitrobenzothiophene-1-oxide (3 and 4) is described. Several racemic aryl methyl carbinols in the presence of 3 or 4 give different chemical shifts for enantiomeric CH, CH3 and OH protons. These chemical shift differences are larger than those observed in analogous sulfoxide-alcohol pairs without nitro groups. Quinine and cinchonidine cause observable non-equivalence of methylene and aromatic protons in racemic 4. The magnitude of the diastereomeric shift difference is sensitive to temperature, solvent, concentration, nature of the π system and steric effects.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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