ISSN:
1432-1076
Keywords:
Arrhenoblastoma
;
Testosterone
;
Δ4-androstenedione
;
Oestrogens
;
Gonadotrophins
;
Dexamethasone suppression test
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A case of ovarian arrhenoblastoma in a 14-year-old girl is reported. The patient presented with primary amenorrhea, severe diffuse hirsutism, moderate clitorial enlargement and slight decrease in breast size. Hormonal examinations revealed high plasma testosterone and androstenedione levels, normal plasma prolactin, dehydroepiandrosterone-sulphate, 17-alpha-hydroxyprogesterone, urinary 17 ketosteroids and pregnanetriol and low plasma 17 beta oestradiol, oestrone, FSH and LH. Androgen concentrations decreased under dexamethasone suppression test. Following tumour ablation menses occurred spontaneously and normal hormone patterns were observed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00441925
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