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  • 1
    ISSN: 1590-3478
    Keywords: Nuclear magnetic resonance (NMR) ; skeletal muscle histopathology ; Duchenne muscular dystrophy ; congenital non progressive myopathies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario In questo lavoro si riportano i risultati di uno studio sulle malattie muscolari primitive del bambino eseguito nell'ambito del nostro programma per la valutazione delle possibilità diagnostiche del NMR su protoni nelle malattie neuromuscolari. Vengono sottolineate importanti differenze tra la risposta NMR in vitro di muscoli di soggetti normali e di soggetti con miopatie congenite strutturali non progressive e con distrofia muscolare tipo Duchenne.
    Notes: Abstract Report of a study of primary myopathies in children conducted within the framework of our program to evaluate the diagnostic potential of 1 H NMR in muscular diseases. There are substantial differences in the in vitro 1 H NMR response of skeletal muscles between normal children and children with congenital non progressive myopathies and Duchenne muscular dystrophy.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    ISSN: 1590-3478
    Keywords: Nuclear magnetic resonance (NMR) ; skeletal muscle ; histopathology ; denervation atrophy ; spinal muscular atrophies ; peripheral neuropathies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Il lavoro dimostra come la Risonanza Magnetica Nucleare dei protoni può essere usata quale mezzo diagnostico per distinguere tessuti sani e patologici. Si riporta una analisi eseguita “in vitro” su muscoli provenienti da pazienti con malattie muscolari da denervazione. Viene suggerita l'esistenza di una correlazione tra gli aspetti istopatologici del tessuto e la risposta NMR dei suoi protoni acquosi. Le nostre conclusioni hanno attinenza col problema dell'impiego della tomografia NMR nella diagnostica clinica.
    Notes: Abstract This paper deals with the possibility of using proton (1H) NMR as a diagnostic tool for discriminating between normal and diseased tissues. As an example, we analyze in vitro the1H NMR response of muscle from patients with neurogenic muscle diseases. It is suggested that there is correlation between the tissue morphology and some details of the proton relaxation processes. Our findings can be of relevance to a clinical application of NMR tomography.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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