ISSN:
1432-2307
Keywords:
Immunoperoxidase
;
Blood group antigens
;
Carcinoma
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In this study the immunoperoxidase technique was used to demonstrate the blood group antigens A, B and H in normal gastric mucosa and primary and metastatic gastric carcinomas. No clear relationship between tumour differentiation and preservation of blood group antigens was found. In some well differentiated tumours there was a marked loss of blood group substance, whereas in other poorly differentiated tumours, both primary and metastatic, it was easily detectable. In some tumours an inverse relationship between A or B and H activity was noted. This observation is consistent with the theory that in some malignant cells there is a blocking of the normal step-by-step elongation of the carbohydrate portion of blood group substances.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00454832
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