ISSN:
1432-0533
Keywords:
Cerebellum, transneuronal degeneration
;
Cerebellum, lobular sclerosis
;
Hemiplegia, infantile
;
Epilepsy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The problem of crossed cerebellar atrophy is re-examined in the light of an illustrative case, recent literature and the authors' previous experience. There types of lesions emerge from this analysis: (1) transneuronal atrophy of the nuclei pontis and contralateral middle cerebellar peduncle, (2) atrophy of nuclei pontis with secondary transneuronal degeneration of the granular layer of the cerebellar cortex, and (3) lobular sclerosis of the cerebellar folia of a postictal pattern. The pathogenesis of these lesions is discussed in the light of present-day concepts of transneuronal atrophy and degeneration and of the spread of the epileptic impulse. It is concluded that many cases of crossed cerebellar atrophy represent post-ictal and not transneuronal lesions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00685389
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