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  • 1980-1984  (2)
  • Chemistry  (1)
  • Excitation-contraction-coupling  (1)
  • ELISA
  • 1
    Electronic Resource
    Electronic Resource
    The effect of histamine on the smooth muscle cells of the ear artery of the rabbit (1980)
    Springer
    Pflügers Archiv 387 (1980), S. 17-25 
    Details
    ISSN: 1432-2013
    Keywords: Vascular smooth muscle ; Histamine ; Excitation-contraction-coupling ; Perivascular nerves ; Cellular Ca store
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Histamine activates both H1- and H2-receptors in the ear artery of the rabbit. The specific action of these receptor activations on the membrane potential and the force development has been investigated by using the H1-blocking agent mepyramine and the H2-blocking agent cimetidine. H1-activation depolarizes and increases force development, while H2-activation hyperpolarizes and reduces force development. These effects on the force development can occur independently of the changes of the membrane potential. By determining the effect of histamine on tissues which were denervated with 6-hydroxydopamine it was shown that histamine exerts its effect directly on the smooth muscle cells. Na-deficiency depolarizes the smooth muscle cells, but it also reduces the changes of the membrane potential and the force development induced by H1-stimulation. K-free medium prevents the hyperpolarizing effect of H2-activation. As far as the ion fluxes are concerned and H1-activation is found to induce an increased efflux of K while a simultaneous H2-activation only reduces the increase of flux induced by H1-activation. H1-activation induces a release of Ca from the intracellular Ca stores, while H2-activation inhibits this release.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00580839
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Aspects of fire research in Japan (1984)
    New York, NY [u.a.] : Wiley-Blackwell
    Fire and Materials 8 (1984), S. 164-171 
    Details
    ISSN: 0308-0501
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fam.810080308
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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