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A neuropathologic study of Werdnig-Hoffmann disease with special reference to the thalamus and posterior roots (1983)

Shishikura, K. ; Hara, M. ; Sasaki, Y. ; [et al.]

Springer

Acta neuropathologica 60 (1983), S. 99-106

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ISSN: 1432-0533

Keywords: Werdnig-Hoffmann disease ; Sensory involvement ; Thalamus ; Posterior root ; Wrist drop

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The brains of five cases of severe infantile from of Werdnig-Hoffmann (W-H) disease were studied to observe the pathologic changes of sensory neurons and the thalamus. The present study disclosed severe cell loss, chromatolytic degeneration, and empty cell beds of the spinal anterior horn and cranial motoneurons (V, VII, X, XII). Glial bundles were also noted in the anterior roots. In the sensory systems, glial bundles in the posterior roots (2/5), ghost cells in Clarke's column (2/5), and degeneration of the thalamus, mainly in the lateral formation (4/4) were noted. It was demonstrated that not only degeneration of lower motor neurons and glial bundles in the anterior roots, but also degeneration of sensory neurons and thalamus were present in W-H disease. These findings suggested the possibility that W-H disease is a multisystemic disease involving both the anterior and posterior root systems. No sensory involvement was found clinically. Characteristic wrist drop was observed in four cases, two of which also having motor nerve conduction velocity (MCV) delay. On the other hand, MCV of another case without wrist drop was normal. The possibility that wrist drop might be one of the clinical features of peripheral nerve dysfunction was discussed, but further pathologic evaluation of peripheral nerves is needed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00685353

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Hochtemperaturphosphidierung von Eisen-Nickellegierungen mittels Phosphordampf (1982)

Sasaki, Y. ; Iida, Y. ; Yakoo, A. ; [et al.]

Weinheim : Wiley-Blackwell

Zeitschrift für anorganische Chemie 487 (1982), S. 232-240

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ISSN: 0044-2313

Keywords: Chemistry ; Inorganic Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Description / Table of Contents: High Temperature Phosphidation of Iron-Nickel Alloys by Phosphorus VaporA study was undertaken concerning the products and kinetics in the phosphidation of iron-nickel alloys with various ratios of metallic constituents at 700° in phosphorus vapor at 1 atm by a sealed-tube method. X-ray diffraction patterns and an electron microprobe analysis of the products showed that the phosphide-layer structure reaches the expression of NiP2 ∼ Ni6P5/Ni2P, Fe2P/(Fe—Ni alloy). The phosphidations proceeded according to a parabolic rate law for all the compositions of the alloy. A marker experiment indicated that the diffusing species was not phosphorus but metals. The rate constant decreased with an increase in the content of iron in the alloy.

Notes: Reaktionsprodukte und Kinetik bei der Phosphidierung von Eisen-Nickellegierungen verschiedener Zusammensetzung bei 700° in Phosphordampf (1 atm) im geschlossenen Quarzrohr wurden untersucht. Aus Röntgenbeugungsbildern und Elektronenstrahlmikrosondeanalysen der Produkte folgt, daß sich Phosphidschichten von NiP2 ∼ Ni6P5/Ni2P, Fe2P/(Fe—Ni-Legierung) bilden. Die Phosphidierungen an Legierungen aller Zusammensetzungen verliefen nach dem parabolischen Zeitgesetz. Ein Markierungsversuch zeigte, daß nicht der Phosphor, sondern die Metalle diffundieren. Die Geschwindigkeitskonstante nahm mit zunehmendem Eisengehalt der Legierung ab.

Additional Material: 8 Ill.