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  • 1980-1984  (2)
  • Computer simulations  (1)
  • Hyperthermia  (1)
  • 1
    ISSN: 1741-0444
    Schlagwort(e): Cancer ; Hyperthermia ; Programmable calculator
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract The use of whole-body hyperthermia as an adjuvant mode of therapy for metastatic cancer requires an accurate control of core body temperature so that the high temperatures encountered during treatment may be safely employed. Heating of the patient is accomplished by use of high-perfusion water-heated blankets. The temperature of the water circulating through the blankets is regulated by digital feedback control, using patient oesophageal temperature as a reference. A forced air heat exchanger is used to cool the circulating water once the control temperature is reached. Patient core body temperatures are currently being maintained at 41·8°C±0·1°C for time periods of up to four hours.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Medical & biological engineering & computing 22 (1984), S. 564-568 
    ISSN: 1741-0444
    Schlagwort(e): Action potential ; Computer simulations ; Electrical characteristics ; Low pass filters ; Radial decline
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract A modified line source model presented earlier has been used to study the decline of the extracellular single muscle fibre action potential. The muscle tissue is modelled as a low-pass filter. The transfer function of the filter declines more slowly than a first order low-pass filter at low frequencies, but much faster at high frequencies. The cutoff frequency of the filter increases when the anisotropy of the muscle decreases. It also increases proportionally with the propagation velocity of the action potential. The decline of different frequency components obtained from the modified line source volume conductor and a filter model derived from experimental measurements are compared and their differences explained. The modified line source model was found to be identical to the volume conductor model in terms of results and at the same time conceptually simple for applications.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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