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  • 1
    Digitale Medien
    Digitale Medien
    Pulmonary vascular sling with tracheobronchial stenosis and hypoplasia of the right pulmonary artery (1980)
    Springer
    Pediatric radiology 9 (1980), S. 113-115 
    Details
    ISSN: 1432-1998
    Schlagwort(e): Vascular sling ; Pulmonary artery, hypoplasia ; Pulmonary artery, anomalous origin ; Trachea-stenosis ; Pulmonary hypoplasia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We present a case of pulmonary sling associated with tracheobronchial stenosis, and with hypoplasia of the right lung and right pulmonary artery. Radiologic studies showed evidence of pulmonary sling and hypoplasia of the right lung; associated hypoplasia of the right pulmonary artery was also present, but not recognized initially. Narrowing of the distal trachea and right main bronchus was present, not due to compression by the anomalous left pulmonary artery, but to congenital stenosis of the trachea and right main bronchus associated with complete cartilaginous tracheobronchial rings.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00977676
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  • 2
    Digitale Medien
    Digitale Medien
    Histidine residue modification inhibits binding of murine β nerve growth factor to its receptor (1984)
    Springer
    The protein journal 3 (1984), S. 349-356 
    Details
    ISSN: 1573-4943
    Schlagwort(e): diethylpyrocarbonate ; protein conformation ; synthetic peptide ; insulin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract The reaction of the β subunit of murine nerve growth factor (NGF) with diethylpyrocarbonate (DEP) results in the quantitative modification of histidine residues and the loss of binding to rabbit superior cervical ganglia microsomes. No conformational changes accompanied the conversion as judged by fluorescence spectra. Hydroxylamine converted the carbethoxy derivatives back to the unmodified imidazoles and simultaneously restored the capacity of NGF to bind to its receptor. Modification of des (1–9) NGF, from which His-4 and His-8 have been quantitatively removed, results in the same loss in binding activity, suggesting that His-75 and/or His-84 may play an important role in hormone-receptor interactions.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01025171
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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