ISSN:
1420-9071
Keywords:
Fetal development
;
brain, human
;
liver, human
;
aldose metabolism
;
sorbitol pathway
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Aldose reductase, sorbitol dehydrogenase, and glucose-6-phosphate dehydrogenase enzyme activities were studied in human foetal brain and liver at different periods of gestation. Aldose reductase activity in liver disappears after 16 weeks of gestation whereas sorbitol dehydrogenase keeps on increasing in liver as well as in brain. In utero, some glucose metabolism may be mediated through an active sorbitol pathway in human fetuses.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01951922
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