ISSN:
1432-0533
Keywords:
Neuroaxonal spheroids
;
Catecholamines
;
Alzheimer's disease
;
Pontocerebellar degeneration
;
Motor neuron disease
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Neuroaxonal spheroids became evident microscopically after the autopsy of a 45-year-old woman with pigmentation of the globus pallidus suggesting Hallervorden-Spatz disease. In our opinion the fine floccular pigment seen electron-microscopically in many of the axonal spheroids is melanin, an end product of catecholamine metabolism. Neurofibrillary degeneration, senile plaques, and granulovacuolar degeneration in the hippocampus produced a picture of Alzheimer's disease. Pontocerebellar degeneration and motor neuron disease were also observed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00691981
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