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  • 1980-1984  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral pathology & medicine 12 (1983), S. 0 
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An ultrastructural study was carried out to investigate the nature of an eosinophilic material, having the staining properties of amyloid, in a case of calcifying epithelial odontogenic tumour. At the electron-microscopical level, the eosinophilic masses consisted of two types of structure which are probably related. The first type appeared as sheets of fine filaments measuring 10–12 nm in diameter. The second type was in the form of aggregates of lamina densa fragments, probably secreted by the tumour epithelium. These fragments appeared to undergo some loss of electron density and became degraded into fine filaments, having similar thickness and electron density to those forming the filamentous masses. It is concluded from this study that the fine filamentous material is a form of amyloid which results from degradation of lamina densa material.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 70 (1981), S. 157-164 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Both myxoma and fibroma viruses were found to be sensitivein vitro to the effects of phosphonoacetic acid. Detectable myxoma virus replication was inhibited at a drug concentration of 100 µg/ml. Fibroma virus replication was inhibited at a concentration of 500 µg/ml. Because of this difference in sensitivity, myxoma virus was used to infect rabbits to test the efficacy of phosphonoacetic acid in the treatment of a systemic viral disease. Rabbits were given 400 mg kg−1 day−1 of phosphonoacetic acid subcutaneously in two injections. Phosphonoacetic acid-treated animals showed a reduction in the severity of disease. Neither serum viral antigen nor infectious virus could be detected. In phosphate buffered saline-treated animals both serum viral antigen and infectious virus were found. All animals treated with phosphate buffered saline died of myxomatosis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 66 (1980), S. 261-264 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Phosphonoacetic acid and phosphonoformate were examined as inhibitors ofHerpesvirus sylvilagus replication in cultured cells. Both drugs produced significant inhibition at a minimum concentration of 25 micrograms per milliliter.
    Type of Medium: Electronic Resource
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