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  • 1980-1984  (4)
Source
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Evidence for host-cell selection of influenza virus antigenic variants (1983)
    [s.l.] : Nature Publishing Group
    Nature 303 (1983), S. 706-709 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 shows haemagglutination inhibition (HI) reactions of six influenza B viruses representative of 27 strains, isolated and passaged in eggs or canine kidney cell cultures (MDCK)4'5, from specimens collected during a school outbreak of influenza in 1982 (J.S.O. et a/., in preparation). The ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/303706a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Differences in the electrophoretic migration rates of polypeptides and RNAs of recent isolates of influenza B viruses (1981)
    Springer
    Archives of virology 69 (1981), S. 197-207 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The electrophoretic migration rates of structural and non-structural poly-peptides of 38 influenza B viruses isolated in epidemics in 1978–1980 and antigenically closely related to B/Singapore/222/79 virus were compared using high resolution SDS polyacrylamide gels. Thirty of the viruses could be distinguished from the prototype B/Singapore/222/79 virus by electrophoretic migration rate differences in HA, 17 by differences in NP and 27 by differences in mobility of the NS1 polypeptide. Mobility differences of NP, NS1 and HA polypeptides was noted in influenza B viruses isolated in the UK in the same year. In addition, electrophoretic mobility of32P labelled virus RNAs varied for certain UK isolates and indicated heterogeneity in genes 2, 3, 4 and 8 coding for polymerase proteins 2 and 1, nucleoprotein (NP) and non-structural protein (NS1) respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01317335
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Plaquing characteristics of influenza A virus recombinants of defined genetic composition (1982)
    Springer
    Archives of virology 74 (1982), S. 227-232 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The plaque size and morphology of twenty-two influenza A virus recombinants representing seven distinct families were analyzed on MDCK cells. By examination of the genetic composition of the recombinants no relationship could be established between any gene, including those coding for the surface antigens, and the plaque size and morphology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01314716
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Electrophoretic migration rate differences of polypeptides of human influenza A viruses: Partial analysis of the genome of influenza vaccine recombinant viruses (1980)
    Springer
    Archives of virology 65 (1980), S. 277-291 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Electrophoretic migration rate differences were detected in high resolution SDS polyacrylamide gels for nucleoprotein (NP), matrix protein (M), non structural protein (NS1), haemagglutinin (HA) and, less regularly, for the polymerase polypeptides P1, P2 and P3 induced by different influenza A viruses. The technique allowed parental assignation of the corresponding genes in certain recombinant viruses including A/PR/8/34 (H0N1)—A/HK/117/77 (H1N1), A/Okuda/57 (H2N2)—A/HK/119/77 (H1N1) and A/Leningrad/76 (H3N2)—A/Leningrad/46 (H0N1) recombinants, thus considerably extending the technique which had been applied previously to A/PR/8/34—A/HK/68 (H3N2) only. Agreement in gene assignment between three recombinants of the former group and 11 of 17 recombinants in the A/Okuda/57—A/HK/119/77 group was noted when the data obtained using the polypeptide method was correlated with a direct genetic analysis by others using RNA:RNA hybridisation techniques. The polypeptide method appears to have wide application for the initial rapid analysis of influenza A virus recombinants obtained using parents of different influenza subtypes although complete analysis of the total genome requires the use of RNA hybridisation techniques. Two additional virus induced proteins are described, a phosphorylated form of NS 1 and a non structual polypeptide with a molecular weight of 16 K daltons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01314544
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    Paper (German National Licenses)
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