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  • 1980-1984  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 14 (1982), S. 254-258 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary These experiments studied the metabolic formation of a,ω-dodecanedioic acid using the mutant S 76 developed from the wild strain Candida tropicalis 1230 (capable of producing large amounts of a,ω-dodecanedioic acid). Our results show for the first time that 12-hydroxydodecanoic acid was excreted into the medium as a free acid. n-Dodecanol and n-dodecanoic acid were also detected in the n-dodecane medium. The mutant S 76 was able to produce a,ω-dodecanedioic acid using either n-dodecanol or dodecanoic acid as the sole carbon source. Quantitative cahnges in the concentrations of 12-hydroxy-dodecanoic acid and other intermediates were recorded during the formation of a,ω-dodecanedioic acid. S 76 was rapidly able to convert large amounts of 12-hydroxy-dodecanoic acid to a,ω-dodecanedioic acid. The formation of a,ω-dodecanedioic acid from n-dodecane via the sequence n-dodecanol→n-dodecanoic acid →12-hydroxy-dodecanoic acid was confirmed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The metabolic formation of eitherα,ω-dodecanedioic acid orα,ω-tridecanedioic acid from the individual n-alkane, n-alcohol, n-monoacid andα,ω-diol with corresponding carbon chain length using K-carrageenan entrapped mutants S76 ofCandida tropicalis was studied. The immobilized cells of S76 could also directly produceω-hydroxy acid andα,ω-dioic acid fromα,ω-diol. With n-alcohol and n-monoacid as substrate, the amount ofω-hydroxy acid andα,ω-dioic acid produced was also a function of the incubation time. The results demonstrated that in the immobilized cells of S76 the formation ofα,ω-dioic acid from n-alcohol can also run both via n-monoacid and viaα,ω-diol as well as in the normal cells of S76.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 56 (1984), S. 624-625 
    ISSN: 0009-286X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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