ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract 1-Aminoaziridines react with hydrogen sulfide with ring opening to give vic-hydrazino thiols. In the case of 1-amino-2-methylaziridine the reaction proceeds regioselectively with the formation of 2-hydrazino-1-propanethiol. The products of condensation of the latter with carbonyl compounds exist in solution, depending on their structure, in the form of the corresponding perhydro-1,3,4-thiadiazines, (2-mercapto-1-methylethyl)hydrazones, or tautomeric mixtures of these compounds. The thermodynamic parameters of the tautomeric equilibria were determined for several systems from the 1H NMR spectra.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00503531
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