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  • 1975-1979  (11)
  • 1970-1974  (6)
  • 1965-1969  (3)
  • 1945-1949  (1)
  • Polymer and Materials Science  (15)
  • Life and Medical Sciences  (6)
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Schlagwörter
  • 1
    Digitale Medien
    Digitale Medien
    Pharmacologically active polymers, 13Part 12, cf. G. Franzmann, H. Ringsdorf, Makromol. Chem. 177, 2547 (1976).. Elucidation of the tumour affinity of poly[sulfadiazineacrylamide] (1976)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 177 (1976), S. 2669-2674 
    Details
    ISSN: 0025-116X
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Beschreibung / Inhaltsverzeichnis: Poly[sulfadiazinacrylamid] (5) mit 14C-Hauptkettenmarkierung wurde synthetisiert und sein Molekulargewicht viskosimetrisch durch Vergleich mit inaktiven Proben von Poly-[sulfadiazinacrylamid] mit membranosmometrisch ermittelten Molekulargewichten ähnlicher Größe bestimmt.In seinem systemischen Verhalten bei Mäusen zeigte die Verbindung einen polymerspezifisch protahierten Verlauf. Die Ausscheidungsraten des Polymeren waren vernachlässigbar gering, seine Toxizität erheblich. Es wurde im Untersuchungszeitraum in der Leber akkumuliert, aber eine Tumoraffinität zum PC6 Plasmazelltumor bei Mäusen war nicht feststellbar.
    Notizen: Poly[sulfadiazineacrylamide] (5), labeled with 14C in the main chain, was synthesized and its molecular weight viscosimetrically determined by comparison with unlabeled samples of poly[sulfadiazineacrylamide] with similar molecular weights which were determined by membrane osmometry.The material showed a polymer-specific prolongation of its systemic behaviour in mice. Rates of excretion of the polymer were negligibly low, whereas the toxicity was considerable. It was concentrated in the liver during the course of the experiment, but no affinity toward the PC6 plasmacytoma in mice could be detected.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/macp.1976.021770909
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  • 2
    Digitale Medien
    Digitale Medien
    The continuous synthesis of addition polymers with a pricesely controlled average molecular weight and minimum polydispersity (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 13 (1969), S. 1353-1371 
    Details
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: A novel technique for the control of continuous synthesis of addition polymers with precisely controlled average molecular weight and minimum polydispersity has been developed. A control system adjusts the concentration of chain-transfer agent in the reactor feed to compensate for all other upsets, in the reactor inputs: initiator and monomer concentrations, temperature and feed rate. The technique has been evaluated quantitatively on a digital computer using a kinetic model of homogeneous, free-radical solution polymerization. In computational tests, the modeled control system generally held the instantaneous number-average chain length within 1%, and quickly returned it to the desired value in response to a wide variety of upsets. By generalizing the Schulz distributions to include termination by disproportionation, combination and chain-transfer, it is shown that changes in the molecular-weight distribution resulting from the action of the control system are minor.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/app.1969.070130703
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  • 3
    Digitale Medien
    Digitale Medien
    Diffusion of gases through polyurethane block polymers (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 23 (1979), S. 201-214 
    Details
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: The diffusivities of simple gases through a series of polyurethane block copolymers of differing aromatic urethane content and type of soft segment were measured using a quadrapole mass spectrometer as a detecting device. Although an Arrhenius expression generally described the temperature dependence of diffusion in this system, a discontinuity was observed in the Arrhenius plots for some materials, and the discontinuity was found to be related to the onset of the glass transition in the hard domains. Increasing the hard segment content of the materials decreased the diffusivity due to the increase in the activation energy of diffusion. Increasing the soft segment length brought about a decrease in the activation energy with an increase in diffusivity. Polyster urethanes had lower activation energies for diffusion than polyether urethanes of similar hard segment composition. Finally, as the penetrant diameter was increased, a decrease in the diffusivity and an increase in the activation energy was noted.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/app.1979.070230118
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  • 4
    Digitale Medien
    Digitale Medien
    Effect of molecular weight on the tensile strength of glassy plastics (1972)
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A-2: Polymer Physics 10 (1972), S. 571-573 
    Details
    ISSN: 0449-2978
    Schlagwort(e): Physics ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Physik
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pol.1972.160100314
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  • 5
    Digitale Medien
    Digitale Medien
    Observations on the development of the human atrioventricular node and bundleSupported by N.I.H. Grant HL07047. (1978)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 192 (1978), S. 337-350 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: This light microscopic study of the cardiac junctional tissues was based on 27 human embryos, fetuses and postnatal hearts. Evidence was presented that superficial and deep portions of the postnatal AV node were derived from two cellular primordia in the posterior wall of the common atrium at the 6-mm stage. The small right primordia was associated with the right venous valve and gave rise to the loosely organized superficial AV node that extended posteriorly to the coronary sinus ostium. A larger left primordia formed the more compact deep subdivision of the AV node located against the anulus fibrosus. In most postnatal hearts the two subdivisions are partially or completely fused to form the adult AV node. Failure of the nodal primordia to fuse during cardiogenesis may result in two separate nodal cell aggregates above the anulus. The present observations provide a rational explanation for the two AV nodal masses described in the literature and an additional specimen that is illustrated in this communication.An AV bundle was first identified in a 13-mm embryo and appeared to be derived from large clear cells of the posterior AV canal. At 25 mm the bundle formed a broad band across the top of the IV septum and continued into both ventricles. At this stage multiple cell strands penetrated the endocardial cushion to connect the AV bundle to the two nodal primordia. Failure of normal fusion between the AV node primordia and AV bundle can result in a variety of junctional anomalies including congenital heart block.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1091920302
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  • 6
    Digitale Medien
    Digitale Medien
    The impact of rigid spheres on rubber (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 16 (1972), S. 1641-1651 
    Details
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: The applicability of Hertz's theory of impact to the case of rigid spheres colliding with rubber has been studied over a wide range of impact conditions. In general, the theory is adequate; but in many practical cases, the influence of the finite thickness of the sample is significant. Using previously published data on the influence of thickness on static indentation measurements, this effect can be predicted and good agreement with experiment is found. Resilience measurements have been made over a range of impact conditions. The time of impact, rather than its severity as such, was found to be the factor governing the resilience for the unfilled materials studied, provided that there was no slip of the sample relative to its holder. Slippage can occur if the sample is too thin, due to the shear stresses developed at the rear surface, and this results in the observed resilience being anomalously low.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/app.1972.070160705
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  • 7
    Digitale Medien
    Digitale Medien
    The irradiation of vinyl monomers in the presence of paraffin waxes (1973)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 17 (1973), S. 2519-2522 
    Details
    ISSN: 0021-8995
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: The radiation-induced grafting of a series of monomers onto a wide range of paraffin waxes was attempted. Although no grafting could be achieved and only homopolymers were formed, the rates of homopolymerization were greatly enhanced in the presence of the wax. This phenomenon is ascribed to processes of energy transfer from the irradiated wax to the monomer.
    Zusätzliches Material: 2 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/app.1973.070170817
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  • 8
    Digitale Medien
    Digitale Medien
    The atrioventricular node and bundle in the ferret heart: A light and quantitative electron microscopic studyThis work was supported in part by N.I.H. grants HL07047, HL19425, HL19606, CA08231. (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 154 (1979), S. 365-391 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The cells of the atrioventricular (AV) junction in the ferret heart were examined using light microscopy, a wax-model reconstruction and quantitative electron microscopy to determine their organization and characteristics. A series of subdivisions of the specialized tissues of the AV junction was apparent at both the light and electron microscopic levels. A transitional zone was observed interposed between the atrial muscle cells and the AV node. The AV node consisted of a coronary sinus portion, a superficial portion and a deep portion. The AV bundle had a segment above the anulus fibrosus, a segment which penetrated the right fibrous trigone, a non-branching segment below the anulus fibrosus and a branched segment. At the ultrastructural level the AV junctional conduction tissues had fewer irregularly oriented myofibrils than did working atrial myocardial cells. T-tubules, present in atrial muscle cells, were not observed in the modified muscle cells of the AV node and bundle. Conventional intercalated discs also were not observed between the cells of the AV node or the AV bundle.Atrial myocardial cells had the highest percentage of the plasma membrane occupied by desmosomes, fasciae adherentes and gap junctions. The AV bundle cells had the highest percentage of appositional surface membrane and a relatively large fraction of plasma membrane occupied by gap junctions. Cells of the superficial portion of the AV node had the smallest percentage of the plasma membrane composed of gap junctions, desmosomes or fasciae adherentes, as well as the smallest fraction of the cell membrane apposed to adjacent cells. The stereological data indicate that the most useful distinguishing characteristic between atrial muscle cells and conduction cells was that a smaller percentage of the conduction cell sarcoplasm was occupied by mitochondria and myofibrils. The most useful characteristics that could be used to differentiate between the regions of the AV junctional conduction tissues were the amounts and types of surface membrane specializations in the respective cell types.
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1001540305
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  • 9
    Digitale Medien
    Digitale Medien
    The development of the atrioventricular node and bundle in the ferret heartThis work is supported by N.I.H. Grant HL07047. (1979)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 154 (1979), S. 135-150 
    Details
    ISSN: 0002-9106
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The development of the atrioventricular (AV) node and bundle in the ferret heart was examined at the light microscopic level. The AV node develops from two primordia which were first observed in the posterior wall of the common atrium during the stage when the single heart tube convolutes. During septation of the heart, the AV nodal primordia eventually fuse and come to lie at the base of the interatrial septum. The right AV nodal primordium is located below the attachment of the right venous valve to the interatrial septum. The left AV nodal primordium maintains a position anterior to the prospective ostium of the coronary sinus. At 16 days of gestation, large pale cells were seen in the dorsal AV canal. By 21 days of gestation these AV canal cells have been replaced by AV bundle cells. At this time the bundle is continuous with both nodal primordia. At birth the AV bundle is continuous mainly with the component of the AV node that is derived from the right AV node primordium. The anulus fibrosus begins to undergo the greatest developmental change after the AV node and bundle attain their final position in the AV junction. However, the anulus does not completely separate the atria from the ventricles during the later stages of development nor at birth, so that accessory AV pathways are present in the newborn ferret heart. Both the AV node and the AV bundle also demonstrated continuity with the myocardial cells of the interventricular septum in the neonatal heart. During development there was no evidence that rings of specialized tissues at the junctions of the cardiac chambers give rise to any component of the cardiac conduction system.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aja.1001540202
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  • 10
    Digitale Medien
    Digitale Medien
    A report of a case of an anomalous right subclavian artery in man with a rare arrangement of the associated arteries (1949)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 103 (1949), S. 139-149 
    Details
    ISSN: 0003-276X
    Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ar.1091030203
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