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  • 1975-1979  (10)
  • 1970-1974  (10)
  • 1960-1964  (2)
  • 1950-1954  (5)
  • 1935-1939  (4)
  • 1880-1889  (1)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 81 (1977), S. 491-494 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 76 (1954), S. 4472-4473 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Synaptosomes incubated in a physiological saline extrude sodium and take up potassium. As would be expected this process is completely blocked by metabolic inhibitors such as cyanide and iodoacetate. However, when metabolic inhibitors are replaced by ouabain (100 μM) there is an increase in the steady state intrasynaptosomal sodium and chloride content even though there is no change in the potassium content. The increases are prevented when synaptosomes are incubated with metabolic inhibitors in addition to ouabain. There is therefore a ouabain-insensitive process that transports sodium, chloride and concomitantly water into synaptosomes. It appears not to function when the supply of metabolic energy is inhibited. The diuretic furosemide (1 mM) in the presence of ouabain inhibits the entry of sodium and chloride without affecting the intrasynaptosomal potassium concentration. Ethacrynic acid (1 mM) has a somewhat similar effect but in addition appears to damage the synaptosome membrane.Kinetic measurements were made of the uptake of sodium, potassium and chloride under conditions of metabolic inhibition and the permeability constants of the membrane determined. Values of 0.068, 0.117 and 0.032 × 10-6 (cm s-1) were found for the permeability constants of the membrane to (respectively) sodium, potassium and chloride. Measurements of the rate of uptake in the presence of ouabain revealed an inwardly directed sodium and chloride flux of 5-20 pmol cm-2 s-1. Calculation of the fluxes from the steady state ion concentrations also reveals an inwardly directed sodium and chloride flux, though of lesser magnitude. The influx of water is less than would be expected to preserve osmotic equality suggesting that the translocation of sodium and chloride is the primary event. Although its function remains uncertain the flux has a considerable effect on the ion content of synaptosomes.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Ecology, Evolution, and Systematics 5 (1974), S. 115-138 
    ISSN: 0066-4162
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Phytopathology 15 (1977), S. 361-385 
    ISSN: 0066-4286
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Biology
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 87 (1972), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case of tinea nigra occurring in a Caucasoid girl aged 10 is described. The infection was probably contracted in Malaya where she had lived between the ages of 2 and 4½. The course of the infection was chronic and protracted, with a tendency to recur after apparent cure. The mycological features are described and the aetiology is discussed.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Cambridge : Cambridge University Press
    Philosophy 11 (1936), S. 239-240 
    ISSN: 0031-8191
    Source: Cambridge Journals Digital Archives
    Topics: Philosophy
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Cambridge : Cambridge University Press
    Philosophy 10 (1935), S. 154-167 
    ISSN: 0031-8191
    Source: Cambridge Journals Digital Archives
    Topics: Philosophy
    Notes: The problem of suffering is essentially a problem in philosophical theology. For many philosophical systems the phenomena of suffering set no special problem at all. The most influential philosophies of the present age, for example, have almost nothing to say on the subject—and there is no reason why, on their metaphysical; principles, they should say anything. The problem is a relevant one only for those philosophies which claim to be in at least general accord with the “religious interpretation of the universe.” But for them it is crucial. Given a Weltanschauung like that of Absolute Idealism, for which the ultimate principle from which all things derive their being is an Infinite and Perfect Spirit, and it becomes at once a clear obligation to offer some explanation of how we are to reconcile the Goodness of God with the existence in the world of so much suffering which is prima facie just bad. As we all know, the problem is an extraordinarily hard one to solve. But, inasmuch as the religious interpretation of the universe demands its solution as a condition of its own possibility, its importance is proportionate to its difficulty.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Cambridge : Cambridge University Press
    Philosophy 37 (1962), S. 263-268 
    ISSN: 0031-8191
    Source: Cambridge Journals Digital Archives
    Topics: Philosophy
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Cambridge : Cambridge University Press
    Philosophy 25 (1950), S. 114-133 
    ISSN: 0031-8191
    Source: Cambridge Journals Digital Archives
    Topics: Philosophy
    Notes: I have chosen my topic for this evening with an eye to something rather more than its intrinsic philosophical interest. Modern man, as we are all painfully aware, is facing a crisis of peculiar gravity. Perhaps the odds are not so very heavy against a third world war followed by world collapse into anarchy and barbarism. At such a time the philosopher is bound to ask himself whether there is no contribution which his science can make towards the succour of civilization.
    Type of Medium: Electronic Resource
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