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  • 1975-1979  (2)
  • 1970-1974  (1)
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Material
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Year
  • 1
    Electronic Resource
    Electronic Resource
    The role of the thymus in antibody production and in resistance to Japanese encephalitis virus infection (1970)
    Springer
    Archives of virology 29 (1970), S. 32-38 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neonatally thymectomized mice and sham-operated mice were inoculated at various ages with various doses of either commercial vaccine or live Japanese encephalitis virus (JEV). Groups of neonatally thymectomized mice were found to have depressed capacity to produce circulating antibody as measured by hemagglutination inhibition test. Furthermore, it could be noted that the survival rate was high in groups in which the serum conversion rate was high, irrespective of the thymectomy at birth. From the results a humoral type of resistance against JEV infection was suggested as the basis for immunity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01253877
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effects of antimetabolites on the production of tubular structures in vero cells infected with herpes simplex virus type 2 (1979)
    Springer
    Archives of virology 62 (1979), S. 175-187 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Treatment of Vero cells infected with herpes simplex virus type 2 with the proper concentrations of hydroxyurea (HU) reduced the production of infectious virus and markedly increased the accumulation of tubular structures in the nuclei when the drug was added within 6 hours after infection. Similar accumulation of tubular structures in the infected nuclei was also observed when infected cells were treated with phosphonoacetic acid at proper concentrations. The release of HU-treated, herpes simplex virus type 2-infected cells from the drug-induced blocking of synthesis of infectious virus resulted in the marked decrease of tubular structures coincidentally with the beginning of production of infectious virus. The data suggest the possibility that the disappearance of tubular structures may be related to the active production of infectious virus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01317550
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Electron microscope observations on tubular structures in cells infected with herpes simplex virus type 2 (1976)
    Springer
    Archives of virology 50 (1976), S. 159-168 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The fine structure of filamentous structures and lattice-like structures found in herpes simplex virus type 2-infected cells was studied. By specimen tilting experiments, it was demonstrated that the lattice-like structures were the cross-sectional views of the tubular structures and the filamentous structures were the longitudinal sections. The observation in negatively stained preparations of isolated tubular structures revealed that the structure was constructed by regular array of ring shaped elements. A hypothetical model is presented for tubular structures constructed on the basis of the present findings. The tubular structures appeared as early as 6 hours after infection and reached a maximum at 12 hours.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01318010
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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