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Digitale Medien

RAT BRAIN β-GALACTOSIDASES: OBSERVATIONS ON CEREBROSIDE-β-GALACTOSIDASE CATALYSED TRANSGALACTOSYLATION AND COMPARISON OF ASSAY METHODS FOR SPHINGOLIPID HYDROLYSIS (1976)

Carter, T. P. ; Kanfer, J. N.

Oxford, UK : Blackwell Publishing Ltd

Journal of neurochemistry 27 (1976), S. 0

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ISSN: 1471-4159

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: Abstract— A partially purified rat brain preparation, enriched in cerebroside β-galactosidase activity, was found to catalyze the synthesis of labelled galactosyl-ceramide from [14C]oleoyl-sphingosine as acceptor and several β -galactosides as donor. The following compounds in the order of their effectiveness served as galactose donors for this reaction: para-nitrophenyl-β -galactoside (PNP-β -gal), galactosyl-ceramide, lactosyl-sphingosine, lactosyl-ceramide, 4-methyl-umbelliferyl-β -galactoside (4-MU-β -gal). asialo-GM1, galactosyl-sphingosine, GM1 and monogalactosyl-diglyceride. It is believed that this transgalactosylation reaction is probably not a mere reversal of the hydrolytic reaction. Under optimal conditions the quantity of galactosyl-ceramide formed represented 10% of the amount of donor hydrolysed. These observations in conjunction with those on the hydrolyses provide further support for the possible existence of two β -galactosidase isoenzymes involved with the catabolism of GM1 and/or lactosyl-ceramide, and a single form for galactosyl-ceramide. The activity of one isoenzyme can be ‘selectively’ measured simply by modifying the incubation mixture.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb01543.x

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Digitale Medien

Genetic Hazard of Ionizing Radiations (1958)

CARTER, T. C. ; LYON, MARY F. ; PHILLIPS, RITA J. S.

[s.l.] : Nature Publishing Group

Nature 182 (1958), S. 409-409

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] However, Russell and Kelly5 have recently stated that they have found a much lower induced spermatogonial mutation-rate at these loci when the dose of 600 rads was given as caesium-137 -rays at a low dose-rate than when it was given as 250 kV. X-rays at a high dose-rate. This means that for mouse ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/182409a0

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Digitale Medien

Structure of the quenched form of polypropylene (1978)

McAllister, P. B. ; Carter, T. J. ; Hinde, R. M.

New York : Wiley-Blackwell

Journal of Polymer Science: Polymer Physics Edition 16 (1978), S. 49-57

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ISSN: 0098-1273

Schlagwort(e): Physics ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie , Physik

Notizen: X-ray diffraction has been used to further investigate the quenched form of polypropylene. The diffractometer traces were analyzed by a mathematical peak separation procedure which assumed a combined Cauchy and Gaussian shape for the peaks. The results confirmed that the quenched form contains about 60% of amorphous polypropylene. In the remainder, the x-ray diffraction peak positions indicate that the chain helices are arranged in a square array and a cubic or tetragonal symmetry is proposed for this phase. The shape of the x-ray diffractometer peaks indicates a degree of strain in the structure. Crystallite sizes, determined from peak breadths, have been estimated as approximately 30 Å.

Zusätzliches Material: 6 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/pol.1978.180160105

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