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  • 1975-1979  (2)
  • Apomorphine  (2)
  • Antipsychotics  (1)
  • (B. thuringiensis)
Materialart
Erscheinungszeitraum
  • 1975-1979  (2)
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Psychopharmacology 56 (1978), S. 233-234 
    ISSN: 1432-2072
    Schlagwort(e): Stereotyped behaviour ; Apomorphine ; Dopamine receptors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Mice treated with apomorphine tend to adopt a vertical position in a stereotyped manner. A quantal evaluation of this behaviour, taking into account its frequency and duration, leads to a biphasic dose-response curve that reveals opposite actions of the dopamine agonist.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1432-2072
    Schlagwort(e): Climbing behavior ; Dopamine receptors ; Apomorphine ; Antipsychotics
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Mice treated with low doses of apomorphine tend to adopt a vertical position along the walls of their cage. Optimal conditions have been defined to obtain a reliable dose-response relationship. This peculiar behavior appears to be elicited by stimulation of dopamine receptors in the striatum: it is suppressed after coagulation of this structure while it is facilitated when these receptors are made hypersensitive by previous treatments with 6-hydroxydopamine or haloperidol; on the other hand, it is not modified by coagulation of the nucleus accumbens. The relative efficacy of various agonists and antagonists of dopamine receptors have been determined on this test. It appears that this stereotyped behavior might represent a convenient mean to assess the stimulation of striatal dopamine receptors in mice.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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