ISSN:
1432-2013
Keywords:
Renin
;
Efferent Arteriole
;
Feedback Control
;
Macula densa
;
Angiotensin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Plasma renin could be detected in 16 nl of rat plasma by incubating at 50°C, pH 6.2 with 20 μl of a rat renin substrate. In 60 nl samples it could be estimated and differences in concentration of 20% could be detected. Plasma renin concentration was measured in blood from the superficial efferent arterioles of a rat's kidney. The concentrations of renin in different efferent arterioles of the same rat were similar. The renin concentration of efferent arteriolar blood was 361±189 (S.D.) ng Al ml−1 (blood) hour−1 which was not different from the renin concentration of simultaneously taken femoral artery blood (340±217). Plasma renin concentration can be measured in efferent arteriolar blood and will allow the control of renin secretion to be studied.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00583839
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