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  • 1975-1979  (3)
  • Aspergillus parasiticus  (2)
  • Chemical Engineering  (1)
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Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Influence of trace elements and nitrogen sources on versicolorin production by a mutant strain of Aspergillus parasiticus (1979)
    Springer
    Mycopathologia 69 (1979), S. 161-166 
    Details
    ISSN: 1573-0832
    Keywords: Aspergillus parasiticus ; Furobenzofuran ; Versicolorin A ; Versicolorin C
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A mutant strain of Aspergillus parasiticus blocked in aflatoxin biosynthesis accumulates versicolorin A and versicolorin C. The effect of trace elements on the growth and versicolorin production by this strain was studied in a defined medium. The omission of manganese was slightly stimulatory to versicolorin production; when zinc was omitted from the medium, no detectable versicolorins were produced. Experiments on nitrogen sources in a highsucrose medium indicated that fourfold to fivefold increases in versicolorin yields could be obtained by substituting 3 ml/l corn steep liquor or 0.1 M NH4NO3 for the 0.023 M (NH4)2SO3 used previously as the nitrogen source in studies on versicolorin production by this strain. These improved yields will facilitate attempts to accumulate enough versicolorin A and versicolorin C for toxicity and carcinogenicity testing. Chromatographic profiles of mycelial extracts of cultures grown in a defined medium with 0.1 M NH4NO3 as the nitrogen source revealed 2 previously unrecognized compounds. The accumulation of these new metabolites in a mutant blocked in aflatoxin production may indicate that they are biosynthetically related to aflatoxin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00452829
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effect of acetone on production of aflatoxins and versicolorin pigments by resting cell cultures of aspergillus parasiticus (1976)
    Springer
    Mycopathologia 58 (1976), S. 9-12 
    Details
    ISSN: 1573-0832
    Keywords: Aflatoxins ; Versicolorins ; Aspergillus parasiticus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Resting cell cultures of Aspergillus parasiticus were grown in medium containing four different concentrations of glucose, with and without acetone. In addition, the effect of different equimolar concentrations of acetone, acetic acid, ethanol, and sodium acetate was compared at two glucose levels. Aflatoxin and versicolorin pigment production increased in resting cell medium containing increasing concentrations of glucose. In the presence of glucose high concentrations of acetone (1.0 and 0.25 M) inhibited secondary biosynthesis and low concentrations of acetone (0.1, 0.025 and 0.01 M) stimulated secondary biosynthesis of aflatoxins and versicolorin pigments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00493586
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Measurement of structured microbial population dynamics by flow microfluorometry (1978)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 24 (1978), S. 570-577 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Commercial microbiological processes frequently contain dispersed microorganisms which are heterogeneous in their age, size, and composition. Relative protein and nucleic acid contents of individual bacteria in Bacillus subtilis submerged cultures have been measured experimentally using laser flow microfluorometry. Marginal and joint population composition density data and their complex patterns of evolution during batch growth provide an impetus and emerging basis for a new generation of potentially robust mathematical models of microbial systems.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690240403
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    Paper (German National Licenses)
    Fulltext
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