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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 127 (1978), S. 219-226 
    ISSN: 1432-1076
    Keywords: Hemihypertrophy ; Wilms' tumor ; Adrenocortical neoplasia ; Wiedemann-Beckwith syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A girl with hemihypertrophy and hamartomas, now 14 years old, had Wilms' tumor and subsequently developed adrenocortical carcinoma. The occurrence of the two tumors with the signs of an inborn defect of growth control supports the hypothesis that both tumors can be caused by the same etiologic factors, which are also teratogenic. An alternative explanation of induction of the second tumor by previous radio- and chemotherapy is discussed. Possible relationships between our case and the syndrome of Wiedemann and Beckwith are pointed out.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1246
    Keywords: Physical Strain and Stress ; Long-distance March ; Catecholamines ; Glucocorticoids ; Cyclic Nucleotides ; Physische Belastung und Beanspruchung ; Langstreckenmarsch ; Catecholamine ; Glucocorticoide ; cylische Nukleotide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Beanspruchung in Arbeit und Beruf und ihre Auswirkungen auf biochemische Größen stehen seit Jahren zur Diskussion. In vorliegender Studie sollte das Verhalten verschiedener biochemischer Parameter bei physischer Belastung geprüft werden. Wir untersuchten Blut- und Urinproben von 31 Offiziers-anwärten der Bundeswehr vor und unmittelbar im Anschluß an einen Langstrecken marsch von 25 km. Analysiert wurden das Laktat im Vollblut, Noradrenalin, Cortisol und die cyclischen Nukleotide c-AMP und c-GMP im Plasma sowie Adrenalin, Noradrenalin, Vanillinmandelsäure und die 17-Hydroxycorticosteroide im Urin. Signifikante Erhöhungen ergaben sich für die Konzentrationen der Catecholamine und der cyclischen Nukleotide nach der physischen Belastung. Keine signifikanten Abweichungen waren für die Substanzen des Glucocorticoid-Stoffwechsels festzustellen. Die einzelnen Parameter werden hinsichtlich ihrer Relevanz für die Objektivierung physischer Beanspruchung diskutiert.
    Notes: Summary The study presented was performed to evaluate the behaviour of some stress-related biochemical parameters induced by physical stress. We investigated urine and blood samples of 32 graduating officers of the German Bundeswehr before and after a long-distance march over 25 km. The concentrations of lactate in blood, noradrenaline, cortisol and the cyclic nucleotides c-AMP and c-GMP in plasma and adrenaline, noradrenaline, vanillic mandelic acid and 17-hydroxycorticosteroids in urine were determined. Significant elevations were detectable for the concentrations of catecholamines and cyclic nucleotides after the physical work-load. No significant differences were observed for the substances of the glucocorticoid metabolism. The single parameters are discussed in respect to their significance for the objectification of physical strain.
    Type of Medium: Electronic Resource
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