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Transient hypothyroidism associated with prematurity, sepsis, and respiratory distress (1979)

Schönberger, W. ; Grimm, W. ; Gempp, W. ; [et al.]

Springer

European journal of pediatrics 132 (1979), S. 85-92

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ISSN: 1432-1076

Keywords: Transient hypothyroidism ; Neonatal intensive care ; Preterm infants ; Respiratory distress syndrome

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Serial TSH and T4 determinations were performed in sixty neonates admitted to our hospital for neonatal intensive care within a period of three months. Seven patients (12%) showed transient hypothyroidism on the basis of low T4 and high TSH values. Only one of these patients, who had meconium aspiration and pneumonia, did not have the respiratory distress syndrome. In addition, 4 of these patients had sepsis. All of the patients were born before 37 gestational weeks and had birth weight under 2200 g. In addition, two patients of this gestational age and birth weight group had a progressive fall of T4 to extremely hypothyroid values without simultaneous elevation of TSH. Two of the 5 patients who died had histological studies of their thyroids. These revealed colloid-depleted vesicles, desquamated epithelium, and prominent vascularisation of the thyroid. The results of this study show that early recognition and therapy of transient hypothyroidism may be live saving.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00447374

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Über die Autoxydation von Norbornenderivaten (1975)

Duschek, Ch. ; Grimm, W. ; Hampel, M. ; [et al.]

New York, NY : Wiley-Blackwell

Journal für Praktische Chemie/Chemiker-Zeitung 317 (1975), S. 1027-1034

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ISSN: 0021-8383

Keywords: Chemistry ; Organic Chemistry

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Description / Table of Contents: On the Autoxidation of Derivatives of NorbornenenNorbornene, bicyclo[2, 2, 1]2-heptene-5-carboxylic acid methyl ester, bicyclo-[2, 2, 1]2-heptene-5-carbonitril, 5-methylbicyclo[2, 2, 1]2-heptene-5-carboxylic acid methyl ester and dicyclopentadiene are easily oxidized by molecular oxygen; the corresponding exo-epoxides are formed as main products by attack on the norbornene double bond.

Notes: Norbornen, Bicyclo[2, 2, 1]hepten-(2)-carbonsäure-(5)-methylester, Bicyclo[2, 2, 1]hepten-(2)-carbonsäure-(5)-nitril, 5-Methylbicyclo[2, 2, 1]hepten-(2)-carbonsäure-(5)-methylester und Dicyclopentadien werden von molekularem Sauerstoff leicht oxydiert; als Hauptprodukte bilden sich unter Angriff auf die Norbornendoppelbildung die entsprechenden exo-Epoxide.