ISSN:
1432-2013
Keywords:
Bohr effect
;
Blood
;
Birds
;
Carbamino CO2
;
DPG
;
IPP
;
O2 affinity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The Bohr factor, φ=Δ log $$P_{{\text{O}}_2 }$$ /ΔpH, was determined at various levels of hemoglobin O2 saturation ( $${\text{S}}_{{\text{O}}_{\text{2}} }$$ ) in fresh whole blood of the duck. Plasma pH was varied by either changing $$P_{{\text{CO}}_2 }$$ of the blood at constant base excess (CO2 Bohr factor, $$\varphi _{{\text{C0}}_2 }$$ ) or by addition of NaHCO3 and HCl at constant $$P_{{\text{CO}}_2 }$$ (fixed acid Bohr factor, ϕAH). No differences were found between $$\varphi _{{\text{C0}}_2 }$$ and ϕAH at $${\text{S}}_{{\text{O}}_{\text{2}} }$$ levels between 20 and 85%, and there was no saturation dependence of the Bohr factor, its average value being −0.44. It is concluded that in whole blood of this bird species CO2 exerts no direct effect on the O2 affinity of hemoglobin.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00584956
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