ISSN:
1617-4623
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary When a [psi -] strain of yeast mutates to [psi +], the efficiency of suppression by certain ochre suppressors is increased. The [psi +] phenotype is inherited extrachromosomally. There is a nuclear gene, PNM, which, when mutant, causes loss of the [psi +] phenotype. PNM - is dominant to PNM + and a heterozygous diploid gradually loses the ability over successive generations, to produce PNM + [psi +] spores. This paper describes the kinetics of this elimination and the data obtained are discussed in relation to two models of the molecular nature of the [psi] genetic determinant—one considering the [psi] determinant as an autonomous nucleic acid, the other treating the possibility that the [psi] nucleic acid is that which codes for rRNA in the nuclear genome.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00268125
Permalink
