ISSN:
1432-2072
Keywords:
Morphine
;
Dependence
;
Abstinence Syndrome
;
Social Isolation
;
Rats
;
Chronic Isolation
;
Narcotics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Although the effects of differential housing, particularly isolation, on the action of several classes of pharmacological agents have been studied, little attention has been given to this factor in regard to narcotics. The present study involves the effects of long-term social isolation on dependence to morphine produced by pellet implants in rats. When abstinence was precipitated with naloxone, isolated rats demonstrated less jumping and less diarrhea than grouped rats. No differences were found in other signs. In addition, the differences were seen both in isolates developing muricidal behavior and those not developing this behavioral pattern.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00421299
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