ISSN:
1612-1112
Keywords:
High-performance liquid chromatography
;
Spiramycin
;
Separation and determination
;
Pharmaceuticals
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Two chromatographic systems are described to separate and estimate the three major components of the macrolide antibiotic spiramycin. The first system uses a C 18 reversed-phase column with acetonitrile-water-diethyl-amine (50:49.95:0.05) eluent, the second uses a microparticulate silica gel column with a mobile phase composed of the lower layer of a mixture of dichloromethane and n-propanol (96–4) saturated with 5% diethylamine in water.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02261832
Permalink