ISSN:
1573-8221
Keywords:
aggregation of cells
;
cytochalasin B
;
colcemid
;
motion of fibroblast-like cells
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Aggregation of normal mouse fibroblast-like cells, placed on the surface of a Millipore filter, was investigated quantitatively. The addition of 10 μg/ml of cytochalasin B (a substance blocking active cell movements) or 0.1 μg/ml of colcemid (a substance disturbing polarization processes in cells and, consequently, interfering with directional cell movements) completely inhibits such aggregation. The inhibition is reversible—after removal of the agents the cells again aggregate. It is concluded that aggregation of cells in this experimental system requires active cell movement and cellular polarization.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00800167
Permalink
