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  • 1975-1979  (3)
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  • 1
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In neonatal rat liver, AFP is localized only in typical hepatocytes. Their lobular distribution changes throughout the neonatal period. Some AFP+ cells also contain albumin. Less than 5% of AFP+ cells incorporate 3H-thymidine (2-hour pulse). Injections of dexamethasone suppress AFP positivity but not albumin positivity nor 3H-thymidine incorporation. AFP is also localized in typical hepatocytes in newborn rat isolated liver cells or liver explants in culture. During the early phase of AFP induction in rats, by mDAB feeding, AFP is detected in cells smaller than the normal hepatocytes and preferentially situated in periportal areas of the liver.Electron microscope immunoperoxidase localizations in newborn rat liver show that AFP is present on bound ribosomes, in the lumina of rough and smooth endoplasmic reticulum, and in the Golgi apparatus. Direct AFP measurement on isolated organelles confirmed this distribution. It indicates a synthesis and secretion pattern similar to that of albumin.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of biometeorology 22 (1978), S. 263-270 
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract The frequency of bronchial asthma in Nairobi is related to meteorological parameters such as relative humidity, rainfall, dew point temperature, hours of sunshine and dry bulb temperature. Two seasons were taken for study: one cold season (May–August 1975) and one relatively warm season (December 1975–March 1976). It was found that significant correlations occurred at a lag of 2 or 3 days, but not at a lag of 4 or 5 days. Cold and wet weather during the cold season and heat of the day and dryness of the atmosphere during the warm season aggravate asthma in Nairobi.. The frequency of asthmatic attacks is about the same during the two seasons, but the intensity of suffering of a greater majority of patients is more in cold and wet weather than in warm and dry weather. 20–25% of the patients do not feel any relationship between weather and their asthmatic troubles. Nearly twice as many patients suffer from cough with the production of sputum in the cold season than in the warm season. About three times as many patients suffer from bronchospasm in the cold season than in the warm season. Severe asthmatic attacks occur almost equally in both the seasons.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 65 (1978), S. 109-110 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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