ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Distribution and Metabolism of Octadec-9-ynoic acid in RatsOctadec-9-ynoic acid (stearolic acid) fed to rats leads to the metabolic excretion of six dicarboxylic acids with retained triple bond. The main metabolic steps are ω-, β-, and presumably α-oxidation. Feeding of 14C-stearolic acid proves that the α-oxidative steps involves the methyl end of the original acid. It could further be shown that this acid is incorporated partially in the body lipids. To a substantial degree it is totally oxidized and expired as 14C—CO2.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19770600707
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