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  • 1
    Digitale Medien
    Digitale Medien
    Productive T7 infection of Escherichia coli F + cells and anucleate minicells (1977)
    [s.l.] : Nature Publishing Group
    Nature 269 (1977), S. 440-442 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] T7 produces approximately 10,000 times more plaques when plated on an F lawn of E. coli cells compared with F+ lawns. The plaques produced on an F+ lawn are irregular in size and do not contain selected mutant or host-cell-modified phage, as phages isolated from these plaques have no increased ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/269440a0
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  • 2
    Digitale Medien
    Digitale Medien
    Helper function of T7 protein kinase in virus propagation (1975)
    [s.l.] : Nature Publishing Group
    Nature 255 (1975), S. 508-510 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] From the above considerations, one would have expected that the absence of protein kinase would have serious effects on phage development. The contrary was found, however, and the burst size or latent period in infection did not depend on the presence of protein kinase1'2. Furthermore, one widely ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/255508a0
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  • 3
    Digitale Medien
    Digitale Medien
    18. Arteriosklerose: Leistungsbreite der Angiographie (1975)
    Springer
    Langenbeck's archives of surgery 339 (1975), S. 169-174 
    Details
    ISSN: 1435-2451
    Schlagwort(e): Angiography, preoperative ; Angiography, postoperative ; Arteriosclerosis ; Angiographie ; Arteriosklerose ; Prä-, postoperative Angiographie
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Stenose, Verschluß oder aneurysmatische Erweiterung sind angiographische Leitsymptome bei Arteriosklerose. Die Aorto-Arteriographie - entweder durch die direkte Punktion oder indirekt mit Katheter - macht die chirurgisch wichtigen Gefäßprovinzen sichtbar, legt Lokalisation und Ausdehnung des Prozesses fest und ermöglicht die Beurteilung der Funktion der Kollateralen sowie der Ein- und Ausstrombahn. Dies betont die ungemeine Wichtigkeit sowohl der präoperativen Angiographie als auch der Dokumentation des Operationserfolges durch die postoperative Angiographie.
    Notizen: Summary Stenosis, occlusion, and aneurysmatic dilatation are the principle angiographic signs in arteriosclerosis. Aorto-arteriography, either by direct puncture or indirectly via a catheter, permits visualization of all vascular sites of surgical interest, determination of the location and extent of the lesion, and evaluation of the function of the collateral system as well as the inflow and outflow. This stresses the extreme importance of angiography in preoperative planning and postoperative documentation of successful therapy.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01257505
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  • 4
    Digitale Medien
    Digitale Medien
    Refractive damping of Fraunhofer diffraction in light ion-nucleus elastic scattering at high energy (1977)
    Springer
    The European physical journal 282 (1977), S. 163-171 
    Details
    ISSN: 1434-601X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract Angular distributions for elastic scattering of 100 MeV and 140 MeV alpha particles by heavy nuclei are characterized by strong damping of the Fraunhofer diffraction oscillations at large angles. This effect is attributed to refraction by the real part of the alphanucleus potential. It is shown that this can be accounted for through a technical modification of Frahn's closed formalism for strong absorption scattering together with a suitable parameterization of the nuclear scattering coefficients. The result exhibits not only the characteristic filling in of the Fraunhofer minima at large angles, but also a subtle interplay of Coulomb and nuclear effects which produce a characteristic dip and hump in the lower Fraunhofer envelope at smaller angles. It is shown that less structured 180 MeV proton-nucleus elastic angular distributions can also be accounted for. Finally, it is suggested that the refractive damping of the Fraunhofer oscillations does not appear at lower energies because of the masking of refraction by quantal surface reflection from the complex nuclear potential, and it is shown how this effect can be included in the formalism.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01408160
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  • 5
    Digitale Medien
    Digitale Medien
    Rühreffekte bei der Vernetzungspolymerisation-Popcornpolymer-und Gelbildung (1977)
    Springer
    Monatshefte für Chemie 108 (1977), S. 133-139 
    Details
    ISSN: 1434-4475
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract Stirring vinyl acetate—(1 Mol%) divinyl adipate mixtures during polymerization influences the gel formation. Popcornpolymer polymerization influences the gel formation. Popcorn-polymer formation is highly favored. To the contrary the growth of popcorn polymer particles in the stirred system is slowed down. An explanation of this behavior is offered.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00900915
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  • 6
    Digitale Medien
    Digitale Medien
    Comparative morphological investigation on the rabbit's auricle after exposure to CO2- and Nd∶YAG-laser radiation (1977)
    Springer
    European archives of oto-rhino-laryngology and head & neck 217 (1977), S. 487-491 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Laser surgery ; CO2-Laser ; Nd∶YAG-laser ; Irradiation effects ; Cartilage
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary By comparing the effects of CO2- and Nd∶YAG-laser radiation (mainly differing in wave-length by a factor of 10), a surgical instrument suitable for Otorhinolaryngology had to be found. The studies were performed on the rabbit's auricle in order to examine the effect of the laser irradiation mainly on the cartilage. The CO2-laser was found to be more efficient in cutting and caused less extended tissue damage than the Nd∶YAG-laser. The latter seems to be more suitable for soft tissue surgery.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00464470
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  • 7
    Digitale Medien
    Digitale Medien
    Elektrophysiologische Bedingungen der Hörnervreizung (1979)
    Springer
    European archives of oto-rhino-laryngology and head & neck 223 (1979), S. 298-300 
    Details
    ISSN: 1434-4726
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Our investigations on current spread around electrodes showed the following results: 1. In the cochlea, a distinct stimulation is only achievable with distances of less than 0,1 mm between electrodes and nerves to be stimulated. 2. In the eighth nerve, the “selectivity” of electrodes, i.e., the ratio between near-field and far-field potential, can be controlled by variations of the resistance of the grounding path of the site of stimulation. 3. Different waveforms of stimulation as well as constant current-against constant voltage-stimulation lead to a different time-dependance of the potential spread. Two alternative implants are suggested with regard to prevention of relative movements between electrodes and site of stimulation.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01109553
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  • 8
    Digitale Medien
    Digitale Medien
    Deficiency of DNA ligase activity in Fanconi's anemia (1978)
    Springer
    Human genetics 〈Berlin〉 45 (1978), S. 25-32 
    Details
    ISSN: 1432-1203
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary A significant decrease in DNA ligase activity was observed in lymphocytes and fibroblasts of a patient with Fanconi's anemia (FA). This decrease is related to the observed DNA repair deficiency indicated by the delayed closing of repair DNA strands following UV irradiation. Other steps of DNA repair were analyzed in the FA fibroblasts, including endonucleolytic incision of DNA, repair DNA synthesis, and exonucleolytic removal of the photoproducts. No differences were found against control cells. The action of DNA ligase is delayed during replication in the FA cells, as seen by an accumulation of replicative intermediates.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00277570
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  • 9
    Digitale Medien
    Digitale Medien
    Pharmacological properties of tetrahydronorharmane (Tryptoline) (1977)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 298 (1977), S. 83-91 
    Details
    ISSN: 1432-1912
    Schlagwort(e): Tetrahydronorharmane ; Tryptoline ; β-Carboline ; Serotonin ; Dopamine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Earlier in vitro experiments led to the hypothesis that tetrahydronorharmane (THN) modulates the effect of serotonin. This assumption has now been tested in vivo on rats. In addition dopaminergic mechanisms were investigated. Findings in favour of a serotonergic action of THN were: 1. The analgesic effect of THN which was antagonized by 9,10-dihydro, 10-(1-methyl-4-piperidyliden)-9-anthrol, a serotonin-receptor antagonist 2. the hypothermic effect of THN 3. the appetite-reducing effect of long-term treatment with THN. An antidopaminergic effect of THN was suggested by: 1. The motility-reducing effect of THN 2. the antagonistic effect against apomorphine-induced licking movements of acute and chronic treatment with THN and the development of supersensitivity to apomorphine one week after withdrawal of THN. 3. the antagonistic effect of THN against the contralateral turning response to apomorphine in animals with unilateral medial forebrain bundle lesions. The antidopaminergic effects were elicited by lower doses of THN than the stimulation of serotonergic mechanisms. The observed prolongation of hexobarbital sleeping time might be an unspecific effect. A reduction of the elimination rate of the barbiturate was not detected.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00508615
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  • 10
    Digitale Medien
    Digitale Medien
    Nitrofurantoin damages DNA of human cells (1978)
    Springer
    Journal of molecular medicine 56 (1978), S. 405-407 
    Details
    ISSN: 1432-1440
    Schlagwort(e): Mechanismus der antibakteriellen Wirkung ; Pharmakologische Nebenwirkungen ; Diploide menschliche Fibroblasten ; DNA-Reparatur ; Xeroderma pigmentosum ; Nitrofurantoin mechanism of antibacterial action ; Drug side effects ; Diploid human fibroblasts ; DNA repair ; Xeroderma pigmentosum
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Summary Nitrofurantoin causes damage to DNA of cultured diploid human fibroblasts. As a consequence DNA synthesis is blocked. The damage is removed by the normal enzymatic DNA repair system. Xeroderma pigmentosum fibroblasts which are defective in the excision endonuclease fail to repair nitrofurantoin-caused lesions.
    Notizen: Zusammenfassung Nitrofurantoin verursacht Schäden an DNA menschlicher diploider Fibroblasten in Kultur. Dadurch wird die DNA-Synthese gestoppt. Die Schäden werden durch das normale enzymatische DNA-Reparatursystem entfernt. Xeroderma-pigmentosum-Fibroblasten, die defekt in der Exzisions-Endonuklease sind, können die Nitrofurantoin-Läsionen nicht reparieren.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01477295
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