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  • 1
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— The influence of hypercapnia on the metabolism of glutamic acid, aspartic acid, glutamine and GABA in rat brain was studied using three different precursors. Acute hypercapnia induced a fall in the concentration of glutamic and aspartic acid, and a rise in the concentration of glutamine and GABA. Acute hypercapnia had a profound effect on the relative specific radioactivity of glutamine indicating that the excess glutamine, present in the brain in hypercapnia, was synthetized from glutamic acid in the compartment where it could become quickly labelled from butyric and glutamic acid, but not from glucose. This effect was maintained in chronic hypercapnia.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 36 (1977), S. 255-265 
    ISSN: 1439-6327
    Keywords: Exercise ; Blood flow distribution ; Cardiac output ; Myocardial blood flow ; Cerebral blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Regional blood flow was measured with the microsphere method in conscious dogs under resting conditions and during moderate exercise on the treadmill. With respect to total organ blood flow, exercise induced a marked increase in blood flow to the calf muscles and to the myocardium, and a significant decrease in the arterial blood supply to the liver. Slight changes in blood flow to the other organs under study (various skeletal muscles, skin, brain, kidneys, intestine) were not significant. Study of the blood flow distribution within the myocardium showed a slight decrease of the ratio of subendocardial to subepicardial blood flow in the left ventricular free wall in response to exercise, and within the brain there was a relative increase in the blood flow to the cerebellum.
    Type of Medium: Electronic Resource
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