ISSN:
1744-313X
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
,
Medicine
Notes:
The quantitative expression of three allotypes–Glm(1), G3m(5) and G3m(21)–has been studied in normal caucasoid sera. A gene dosage effect, previously described for all of these allotypes, is not noticed for G3m(5) in the present study. The different content of G3m(5) and G3m(21) IgG 3 molecules in heterozygous Gm5/Gm21 sera has been verified: these contents are respectively 75% and 25% of the IgG3 content.The same allotypes have been studied in a family which shows the inheritance of a weak Gm1, 17; 21 haplotype. The gene responsible for this abnormality is probably a new regulatory gene, and is transmitted without the ‘aimed’ haplotype.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1744-313X.1977.tb00923.x
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