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  • 1970-1974  (7)
  • 1965-1969  (6)
  • Chemical Engineering  (6)
  • Life and Medical Sciences  (5)
  • Amitriptyline-Perphenazine  (1)
  • Avoidance  (1)
Material
Years
Year
  • 1
    ISSN: 1432-2072
    Keywords: Chlorpromazine ; Chlordiazepoxide ; Avoidance ; Anxiety ; Escape
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Squirrel monkeys were presented with two stimuli in alternation, separated by time out periods during which neither was present. One was white noise accompanied by irregularly spaced pulses of shock, the other continuous shock at a lower intensity. Following an interval of time which varied in an unpredictable sequence, the next depression of the response lever turned the stimulus off. The schedule on which termination was possible was identical for the two stimuli, and the intensity of the continuous shock was adjusted to a level that produced approximately equal frequencies of pressing, typically from 40 to 80 responses per minute. Doses of chlordiazepoxide ranging from 2.5 to 10.0 mg/kg, i.p., produced a significantly greater decrease in the rate of response in the presence of the continuous shock than in the presence of the noise. On the other hand, doses of chlorpromazine ranging from 0.25 to 1.0 mg/kg, i.p., produced no differential effect. Previous findings of selective action on behavior that terminates signals paired with shock (avoidance) may be related to differences in experimental contingencies or in the pre-drug strength of the two performances compared, rather than to the effect of chlorpromazine on an experimental analogue of human anxiety.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2072
    Keywords: Doxepin ; Amitriptyline-Perphenazine ; Initial Depression ; Setting Effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Doxepin was compared to the combination of amitriptyline-perphenazine in a double-blind controlled study conducted with 100 clinic, general practice, and private psychiatric practice outpatients diagnosed as suffering from a mixed anxiety-depressive reaction. The relatively few statistically significant differences found in the study indicated amitriptyline-perphenazine to be more effective than doxepin (main drug effects), general practice patients to improve the most and private psychiatric patients the least (main population effects), and clinic patients to respond better to doxepin, while general practice and private psychiatric patients improved most with the drug combination (drug×population interaction effects). Amitriptyline-perphenazine was found to produce more improvement in high and doxepin in low depressed patients, and doxepin was observed to be more effective in lower than in higher social class patients. Patients on doxepin tended to report more side effects, but to drop out less frequently than patients on the drug combination.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 133 (1971), S. 273-280 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The cloacal sacs of Leptotyphlops dulcis are nonglandular, posterior evaginations of the cloaca. The median cloacal gland is tubuloalveolar. Similar unpaired cloacal glands as well as paired sacs are noted in certain colubrid snakes. Terminology applied to these cloacal derivatives is discussed, and a standardization of names is provided.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 14 (1968), S. 415-420 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A packed bed model has been adopted to develop a general correlation applicable to the flow of Newtonian fluids through all types of woven metal screens. Both of the main theoretical approaches to studying pressure drop in packed systems have been used by visualizing the screen as a collection of submerged objects with surface area to unit volume ratio a for laminar flow, and as a bundle of tubes of diameter D for turbulent flow. In the usual manner viscous and inertial energy losses are added to give an expression for the total pressure loss. Rearrangement of the general equation to the form of a friction factor yields a unique definition of the Reynolds number for screens NRe = ρu/μa2D. Procedures are described for collection of pressure drop-velocity data for the flow of nitrogen and helium through plain square, full twill, fourdrinier, plain dutch, and twilled dutch weaves. The data are used to derive a viscous resistance coefficient α = 8.61 and an inertial resistance coefficient β = 0.52. The validity of the correlation equation is tested by using additional data from the literature. The correlation successfully predicts pressure drop for a Reynolds number range of 0.1 to 1,000, void fractions from 0.35 to 0.76, screen pore diameters from 5 to 550 μ, mesh sizes from 30 to 2,400 wires/in., and surface area to unit volume ratios from 1,200 to 29,000 ft.-1.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 16 (1970), S. 483-489 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A flow visualization study was made with an optically birefringent solution of milling yellow dye in water flowing through a transparent duct of isoceles triangular cross section. The present data confirm a number of theoretical predictions concerning transitional phenomena in triangular ducts. One of the most interesting of these phenomena is the existence of a region of simultaneous laminar and turbulent flow in the duct. The present results, which agree with the theory, indicate an order of laminar and turbulent flow which is inverse to previous observations made with smoke filament tracings.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 16 (1970), S. 620-625 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An extensive numerical study was carried out to determine the effect of Lewis number on the stability of a chemical reaction occurring inside a porous catalyst pellet. It is found that when the Lewis number is different from 1, the coupling between the concentration and temperature causes several pathological effects during the transient periods. One of the most interesting phenomenon is the occurrence of a unique unstable steady state with a periodic appearance of a very hot spot.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 12 (1966), S. 986-994 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Capillary phenomena arising from vapor phase condensation in porous media are discussed in the light of an exact interface curvature theory and a self-consistent thermodynamic theory. The system studied consists of liquid condensed in the form of pendular rings at the contact points between identical spherical particles. The geometrical parameters - the curvature, the confined volume, and the surface area of the liquid-vapor interface - must be expressed in terms of incomplete elliptic integrals. In addition several corrections are introduced for the classical Kelvin relation for lowering of vapor pressure. One of these is based on the density dependence of the isothermal thermodynamic susceptibility. Since the susceptibility vanishes at large negative pressures, an upper limit to the curvature is established. The balance equation for the extensive free energy is considered from the point of view of hydrostatic principles.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 13 (1967), S. 657-662 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: This paper presents theoretical studies of a method of using a radioactive tracer technique to evaluate the kinetic data of heterogeneous catalytic reactions that are coupled with a Knudsen type of pore diffusion. By superimposing a transient radioactive tracer response over the steady state concentration profile in the catalyst particle, one can establish an implicit relation between the total amount of radioactive components diffused out of the particle and the kinetic data of the reaction system. This relation can then be used to evaluate kinetic data of the reaction system. A detailed study of general monomolecular complex systems is given. Use of the method for nonlinear systems is also included.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 19 (1973), S. 901-909 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effectiveness of the stationary form of the discrete Kalman filter for state estimation in noisy process systems was demonstrated by simulated and experimental tests on a pilot plant evaporator. The filter was incorporated into a multivariable, computer control system and resulted in good control despite process and/or measurement noise levels of 10%. The results were significantly better than those obtained when the Kalman filter was omitted or replaced by conventional exponential filters. In this application the standard Kalman filter was reasonably insensitive to incorrect estimates of initial conditions or noise statistics and to errors in model parameters. The filter estimates were sensitive to unmeasured process disturbances. However this sensitivity could be reduced by treating the noise covariance matrices R and Q as design parameters rather than noise statistics and selecting values which result in increased weighting of the process measurements relative to the calculated model states.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 159 (1967), S. 159-169 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Horseradish peroxidase was injected into the spleens of mice and the animals were sacrificed ten minutes after injection. The tissues were reacted with 3-3′ diaminobenzidine hydrochloride and the distribution of the reaction product was studied with both the light and electron microscope. The peroxidase was localized between epithelial cells up to the region of the tight junction and within vacuoles in the absorptive cells Granules ranging in size from ca. 40A to 600A were observed in the cytoplasm of epithelial cells in numbers far in excess of that found in control specimens. It appeared that the diffuse light brown staining observed in epithelial cells with the light microscope could be attributed to large numbers of granules of reaction product free in the cytoplasm. When corn oil was given by stomach tube and an intravascular injection of perioxidase was given ten minutes later, absorbed lipid was found to pass from interepithelial cell spaces to lamina propria at the same time that peroxidase was traversing the same compartments in the reverse direction. Hence, it was shown that exogenous peroxidase and probably other substances of vascular origin required for the metabolism of epithelial cells are exposed to both the basal and lateral epithelial cell membranes, even when absorbed lipid is traversing the same spaces in the opposite direction.
    Type of Medium: Electronic Resource
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