ISSN:
1432-2072
Keywords:
Hippocampus
;
Magnesium Pemoline
;
Memory
;
Bar Press Extinction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Stainless steel cannulae were implanted in the medial hippocampus of 24 rats. The subjects were then trained to press a bar for milk reinforcement. After a fixed amount of training the animals were divided into four groups. A control group received injections of Holman's ringer (via the cannulae) while each of three experimental groups received a different dose of magnesium pemoline. The animals then performed an additional number of bar presses. Twenty-four hours later the time and number of bar presses to an extinction criterion were measured. The low and medium drug-dose group exhibited increased resistance to extinction. The results were discussed with regard to the effect magnesium pemoline has on performance variables and RNA synthesis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00439374
Permalink
