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  • 1970-1974  (2)
  • 1910-1914
  • Cyclic AMP  (1)
  • sedimentology  (1)
  • 1
    ISSN: 1432-1912
    Keywords: Lipolysis ; Adenyl Cyclase ; Phosphodiesterase ; Glucocorticoids ; Cyclic AMP ; Cortisone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of adrenalectomy and cortisone replacement in rats on the activities of adenyl cyclase and phosphodiesterase in homogenates of isolated fat cells and on the accumulation of cyclic 3′,5′-AMP in intact cells were studied. 1. Adrenalectomy caused a decrease in the activity of norepinephrine- and fluoride-stimulated adenyl cyclase in homogenates of isolated fat cells. This decrease was not significantly reversed by pretreatment of the animals with cortisone in vivo. 2. Adrenalectomy caused an increase in the activity of phosphodiesterase. This increase was not reversed by pretreatment of the animals with cortisone for 4 h in vivo but was reversed after 18 h. Incubation of cells from adrenalectomized animals with cortisone in vitro caused no change in phosphodiesterase activity. 3. The incorporation of prelabelled nucleotides into cyclic 3′,5′-AMP was significantly reduced in intact cells from adrenalectomized rats. Pretreatment of the animals with cortisone in vivo for 4 h completely restored the ability of the cells to accumulate radiolabelled cyclic 3′,5′-AMP upon stimulation by norepinephrine. The experiments underline the difficulties in comparing activation patterns of enzymes under optimal conditions with those occurring in the intact cell. The nature of the lesion in lipolysis caused by adrenalectomy and the reversal of this lesion by cortisone replacement can be demonstrated in the intact cell only.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical geology 4 (1972), S. 219-234 
    ISSN: 1573-8868
    Keywords: factor analysis ; sedimentology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Mathematics
    Notes: Abstract Factor analysis using promax oblique rotation was used in a study of fluvioglacial sediments of Late Weichsilian (Wurm) age. The use of oblique rotation allowed a more realistic interpretation of the factors and understanding of relationships between sedimentsize classes. At the second-order level, two factors are operatable, one producing variations in the coarse-size range, the other in the fine-size range. The factors are uncorrelated and mutally unrelated. At the first-order level are six factors, four representing aspects of the second-order factor of coarse size and two representing the fine size. The factor producing the variation in the coarse size is the most important one. At the lowest level in the hierarchy scale are the individual size variables. Results show that the number of factors required to account for the variation in a sediment-size data set is a function of the scale at which the problem is examined.
    Type of Medium: Electronic Resource
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