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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 86 (1972), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 89 (1973), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Water loss and carbon dioxide release measurements were performed to determine whether the severity of damage to human skin, caused by exposing its surface to buffered and unbuffered solutions of alkali and sodium phosphate, could be evaluated simultaneously by means of different measuring techniques and whether the results of these measurements, expressed in numerical terms, gave identical information.It appeared that the buffered solutions disturbed skin functions less than the unbuffered solutions and therefore may be considered to be less harmful. The NaOH solution at pH 12.0, lacking any buffering capacity, damaged the skin, producing signs of inflammation, whereas that at pH 10.0 did not.It appeared that skin damage could be assessed reliably by simultaneously measuring changes in skin impedance, water loss and carbon dioxide release, which are interrelated parameters.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 89 (1973), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The impedance of human skin was measured at a frequency of 25 Hz and 0.032 mA before, during and after exposing 6 cm2 skin for 60–240 min to 10 or 12 ml of alkali (NaOH and sodium phosphate) and sodium chloride solutions, adjusted to different pHs. From the impedance and phase angle values, measured at intervals of 10–60 min between different pairs of skin sites, the changes in the single transition resistances of these skin sites were calculated.Sodium hydroxide (NaOH) solution at pH 12.0, within 10 to 15 min, abolished skin resistance completely; a solution of sodium phosphate, adjusted to the same pH, affected skin resistance similarly, but only after 60 minutes.The order of severity in skin effects of solutions of other alkaline substances, adjusted to different pHs was determined.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 86 (1972), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.— In search for rapid routine methods for the measurement of carbon dioxide release by human skin, the authors succeeded in improving the infrared analytical method which, when carried out at 4·3 μm, yielded reliable results. Two techniques have been compared, viz. the steady state method (for larger skin areas of about 8 cm2) and the trap technique (which is less dependent on the area to be measured: 1 to 10 cm2).With both techniques micro amounts of carbon dioxide, eliminated by very small areas of the skin and/or the sweat glands, can be determined: 2 to 100 parts/106 of CO2 10 cm-2 min-1.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 9 (1973), S. 261-277 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Polyinosinic acid [poly(I)] was studied by a variety of techniques and together with the results in the literature the following structures are proposed. 1. CD spectra of poly(I) as a function of ionic strength, temperature andpH show the existence of three main forms. At neutral pH and low ionic strength (below 0.1 M NaCl) at 3 °C or 20 °C poly(I) is a single-stranded poorly stacked helix. At 3 °C above 0.6 M NaCl poly(I) forms a multi-stranded (probably four-stranded) parallel left-handed helix. At 20 °C this structure is not completely formed. Between these extremes of ionic strength mixtures of the two forms are present which evolve differently with time, depending on ionic strength and temperature. 2. The acid titration of poly(I) shows three regions as a function of ionic strength, following the same pattern as the CD spectra. The ionic strength dependence of thepK. (∼1.5) above 0.6 M NaCl suggests, but does not prove that N7 of the hypoxanthines may be implicated in the hydrogen-bonding scheme. Similarly, at high ionic strength methylation on N7 is greatly reduced in rate and extent. 3. It is shown that the X-ray fiber pattern of Rich could be interpreted by a fourstranded helix withM=23/2 using a hydrogen bond between N1 and N7 between neighbouring bases.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Zoomorphology 69 (1971), S. 9-22 
    ISSN: 1432-234X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Terrestrial crustaceans have larger eyes, more ommatidia and smaller angles of ommatidial divergence than their nearest aquatic relatives. The speed of the eyes, as calculated from anatomical data, is greater in aquatic than in terrestrial Crustacea. These adaptative changes have taken place independently in different lines of Amphipoda, Isopoda, Anomura and Brachyura.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 44 (1974), S. 191-192 
    ISSN: 1432-2242
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 44 (1974), S. 381-382 
    ISSN: 1432-2242
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1939
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung An Wildfängen und Laboratoriumstieren von Agonum assimile Payk. wurde durch Sektionen und Fortpflanzungsexperimente die Steuerung der Jahresrhythmik untersucht. A. assimile ist ein Frühlingstier mit Sommerlarven. Die Käfer schlüpfen von Juli bis September, überwintern und pflanzen sich im nächsten Frühling von April bis Juni fort. Die alte Generation stirbt im Winter zum Teil ab. Die vorjährigen Tiere machen etwa die Hälfte der sich fortpflanzenden Käfer aus. Die Aufzucht im Laboratorium bis zur Imago gelingt mit etwa 80–90% Zuchterfolg und hängt von der Qualität der Nahrung ab. Im Laboratorium erfolgt die Reifung beider Geschlechter bei 20°C und Langtag dischron (Verzögerung bei den Männchen) und its potentiell dormanzfrei. Die Entwicklung der weiblichen und männlichen Gonaden wird hauptsächlich photoperiodisch gesteuert und bei abnehmender Photoperiode in unterschiedlicher Weise gehemmt (photoperiodische Quieszenz). Dadurch wird im Herbst eine Reifung der Weibchen verhindert und ein langsames Heranreifen der Männchen im Winter ermöglicht. Die Beendigung der Quieszenz durch Übergang von Kurztag zu Langtag im Laboratoriumsexperiment oder bei zunehmender Tageslänge im Frühling läßt beide Geschlechter synchron zur Reife gelangen. Die Weibchen bringen in der Regel 20–60 Larven hervor. Es gelang, Laborzuchttiere bis zu 3 Jahren zu halten und dabei mehrmals zur Fortpflanzung zu bringen.
    Notes: Summary The control of annual rhythmicity in Agonum assimile was investigated by dissections and by breeding experiments both with specimens captured in the field and these reared in the laboratory. A. assimile is a spring breeder with summer larvae. The beetles hatch from the pupa from July until September, hibernate and breed in the following spring from April until June. Only a part of the old generation dies during the winter. Beetles from the previous year form about half of the breeding population. Rearing to the adulthood under laboratory conditions is possible with a success of about 80–90%, depending on the quality of food. Maturation of the sexes in the laboratory is desynchronized when the beetles are kept at 20°C and under “long day” conditions; development of the males is delayed in this case. In both sexes maturation takes place potentially free of dormancy. Development of the female and male gonads is mainly under the control of photoperiod and retarded in different ways by decreasing day length (photoperiodic quiescence). Thereby a maturation of the females is hindered in the autumn, and slow, further development of the males during the winter is made possible. The termination of quiescence by the transition from the “short day” to “long day” in laboratory experiments, or by increasing day length in the spring, synchronizes complete development in both sexes. The females normally produce an offsping of 20–60 larvae. We succeeded in keeping laboratory bred specimens up to 3 years, over this span they could be brought to propagation several times.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 48 (1970), S. 1308-1311 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Capillary-migration-inhibition test using peripheral blood leucocytes was performed in 23 patients with rheumatoid arthritis and in 11 control subjects. In these in vitro-studies synovial extracts caused a significant inhibitory effect on leucocyte migration in rheumatoid arthritis patients. The possible role of delayed type hypersensitivity in the pathogenesis of rheumatoid arthritis has been discussed.
    Notes: Zusammenfassung Bei 23 Patienten mit primärchronischer Polyarthritis (PCP) sowie bei 11 Kontroll-personen wurden Untersuchungen mit dem Migrations-Inhibitionstest (MIT) durchgeführt. Es zeigte sich bei diesen in vitro-Studien, daß homologe Synovial-extrakte die Migrationsfähigkeit der Leukocyten von PCP-Patienten deutlich beeinträchtigen, während dies bei den Kontrollpersonen nicht der Fall war. Die Unterschiede sind statistisch hoch signifikant. In Anbetracht dieser Ergebnisse wird die Bedeutung celluläerer Immunreaktionen in der Pathogenese der PCP diskutiert.
    Type of Medium: Electronic Resource
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