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  • 1970-1974  (4)
  • Polymer and Materials Science  (2)
  • Calcium Oxalate Crystals  (1)
  • DNA-Schaden  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Therapie-bedingte Form einer reno-cerebralen Oxalose? (1974)
    Springer
    Acta neuropathologica 27 (1974), S. 181-184 
    Details
    ISSN: 1432-0533
    Keywords: Calcium Oxalate Crystals ; Toxic Changes of Brain Vessels ; Toxic Meningoencephalitis ; Oxalate Metabolism ; Xylitol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Within a short period of time, we observed 6 cases with the appearance of calcium oxalate crystals in the renal tubuli and in the walls of cerebral arterioles. Reviewing the case histories showed that all of these patients had received large doses of xylitol and had shown subsequently disorders of consciousness. A possible deposition of oxalate crystals following high-dose-therapy with xylitol is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00687169
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Möglichkeiten zur gezielten Diagnose durch Bestimmung der sauren Desoxyribonucleasen im Urin gesunder Kontrollpersonen und Xeroderma pigmentosum-Patienten (1971)
    Springer
    Journal of molecular medicine 49 (1971), S. 1290-1294 
    Details
    ISSN: 1432-1440
    Keywords: Deoxyribonucleases ; diagnosis ; DNA-damage ; microdiscelectrophoresis ; repairmechanism ; urine ; Xeroderma pigmentosum ; Desoxyribonucleasen ; Diagnose ; DNA-Schaden ; Microdiscelektrophorese ; Repairmechanismus ; Urin ; Xeroderma pigmentosum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Das Verteilungsmuster der DNase-Aktivität1 im Urin von Normalpersonen und X.p.-Patienten wurde mit einem mikro-disk-elektrophoretischen Verfahren untersucht. Bei saurer Inkubation sind 4 distinkte Aktivitätsbanden im Normalurin nachweisbar. Urin von X.p.-Patienten zeigt eine deutliche Verminderung der 2.–4. Bande, wobei die Veränderung der 3. Bande besonders auffällig ist. Es wurde ferner untersucht, wie sich das Verhalten verändert, wenn statt nativer DNA denaturierte als Substrat angeboten und wenn die zweiwertigen Ionen durch EDTA komplexiert wurden. Eine Aktivitätsverminderung ist nicht auf das Auftreten von Inhibitoren zurückzuführen, sondern wahrscheinlich durch eine Konzentrationsverminderung an Enzym verursacht.
    Notes: Summary The distribution pattern of desoxyribonuclease (DNase) activity1 in the urine of healthy subjects and xeroderma pigmentosum (X.p.) patients has been examined by micro disc electrophoresis. When incubated at pH 5.0, four distinct bands of DNase activity are shown in normal urine. In urine of X.p. patients a significant decrease of the second to fourth band can be observed. The change of the third band is extremely obvious. Further to the influence of native DNA, denaturated DNA and EDTA on the pattern of DNase activities were studied. The decrease of DNase activity in X. p. urine is not due to the presence of an inhibitor but is rather caused by lower enzyme concentrations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01733085
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    α-Substituted diisopropylbenzene hydroperoxides for low-temperature SBR polymerizationPresented before the Rubber Division of the American Chemical Society, Boston, Massachusetts, April 25-28, 1972. (1973)
    New York : Wiley-Blackwell
    Journal of Polymer Science: Polymer Chemistry Edition 11 (1973), S. 1589-1600 
    Details
    ISSN: 0360-6376
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Four pure hydroperoxides were evaluated as initiators for the polymerization of styrene-butadiene rubber (SBR) at 5°C. These materials were the meta and para isomers of mono- and dihydroperoxy-diisopropylbenzene. Results showed that the monohydroperoxides produced somewhat faster reactions than a control hydroperoxide, p-menthane hydroperoxide. Response to mercaptan level adjustments was good, providing polymer with a Mooney viscosity in the 50 to 60 range. The reaction rate with the dihydroperoxides was slower, but again provided polymer with a satisfactory viscosity. Basic physical property measurements on polymers prepared with the pure hydroperoxides or control hydroperoxides showed only minor differences. It is anticipated that these differences can be eliminated by small adjustments in the compound recipe.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1973.170110709
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  • 4
    Electronic Resource
    Electronic Resource
    Die wechselwirkung der desoxyribonucleinsäure mit dem actinomin nach röntgenkleinwinkelmessungenErweiterte Fassung vom 8. Juni 1970. (1970)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 139 (1970), S. 83-102 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: The interaction of Na-DNS and actinomine in diluted aqueous NaCl solutions is investigated by means of small angle X-ray scattering. Ultrasonic degradation of high molecular DNS yielded particles of suitable length so that besides the cross section also the particle length could be determined. DNS solutions saturated with actinomine have been measured down to a DNS concentration of 0,045 g/100 ml. We observed an extension of the DNS fragments after interacting with actinomine by 18%. The amount of actinomine in the addition compound has been determined: As an average, 7.1 base pairs are combined with one actinomine molecule. Also a shell of counter and by ions surrounding the DNS particles has been found and its dimensions have been determined. From the pseudo cross section scattering curves the inner parts of the cross section scattering curves valid for infinitely long particles could be reconstructed as calculations proceeded.
    Notes: Es wird die Wechselwirkung von Na-DNS und Actinomin in verdünnten, wäßrigen NaCl-Lösungen mit den Methoden der Röntgenkleinwinkelstreuung untersucht. Dafür mußten aus hochmolekularer DNS durch Ultraschallabbau Teilchen geeigneter Länge hergestellt werden, so daß neben dem Querschnitt auch die Teilchenlänge mit der Röntgenkleinwinkelstreuung noch zu erfassen war. Die Messungen erfolgten an mit Actinomin gesätigten DNS-Lösungen bis herab zu einer DNS-Konzentration von 0,045 g/100 ml. Es konnte dabei eine Streckung der abgebauten DNS-Partikel bei Anlagerung von Actinomin um 18% festgestellt und die Menge des an die DNS gebundenen Actinomins bestimmt werden: im Mittel wird auf 7,1 Basenpaare ein Actinomin-Molekül angelagert. Gleichzeitig wurde eine die DNS-Partikel umgebende Hülle aus Gegen- und Bei-Ionen durch Beugung festgestellt und deren räumliche Dimension ermittelt. Im Verlauf der Auswertung ist es auch gelungen, aus den vorliegenden Pseudo-Querschnittsstreukurven die für unendlich lange Teilchen gültigen Querschnittsstreukurven-Innenteile zu rekonstruieren.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1970.021390107
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