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  • 1970-1974  (2)
  • Cerebellum  (1)
  • Instrumental Conditioning  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 17 (1973), S. 50-62 
    ISSN: 1432-1106
    Keywords: Cerebellum ; Barbiturates ; Unitary activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In precollicular decerebrate cats, limb nerves have been stimulated and field potentials and unitary activity recorded from the cerebellar cortex. Doses of pentothal up to 8 mg/kg affect neither the activity evoked in the fast mossy fibre pathways, nor the size of the postsynaptic potentials in granule cells, but the axon discharge in these latter cells is clearly affected. With 4–8 mg/kg the axon discharge of granule cells is abolished and as a consequence Purkinje cells do not respond to the peripheral stimulation via the mossy fibres. In contrast the activity evoked through the climbing fibres is enhanced. This effect takes place at precerebellar level. Both the effects on the mossy fibre and climbing fibre pathways show a recovery in 15–60 min depending on the dose.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: Cerebellärer Cortex ; Instrumentelle Konditionierung ; Licht-Dunkelheit-Diskrimination ; Cerebellar Cortex ; Instrumental Conditioning ; Light-Dark-Discrimination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Eighteen cats were used as subjects in a study which investigated the effects of bilateral cortical cerebellar hemispheric ablations upon light-dark discrimination learning. From the operated control group (8 animals), 5 were tested two weeks and 3 three weeks postoperatively. From the experimental group (10 animals) 4 were tested two weeks and 6 three weeks postoperatively. The discrimination task consisted of an instrumentally conditioned bar-pressing response. The results showed that almost during the entire 23-day learning period, the experimental cats performed more poorly on the discrimination task than their controls. It is hypothesized that the difference between the two groups of animals derives from the disturbance (caused by the ablation) of the connections between the cerebellum and other structures involved in the habituation process.
    Notes: Zusammenfassung 18 Katzen wurden als Versuchstiere in einem Experiment benutzt, welches den Einfluß der bilateralen Entfernung des corticalen Teils der cerebellären Hemisphären auf das Erlernen einer Licht-Dunkelheit-Diskrimination untersuchte. Von der operierten Kontrollgruppe (8 Tiere) wurden 5 zwei Wochen und 3 drei Wochen nach der Operation getestet. Von der experimentellen Gruppe (10 Tiere) wurden 4 zwei Wochen und 6 drei Wochen nach der Operation getestet. Die Diskriminationsaufgabe bestand aus Hebeldrücken nach der Skinner-Methode. Die Ergebnisse zeigten, daß die experimentellen Tiere fast während der ganzen Lernperiode (23 Tage) weniger Diskriminationsvermögen aufweisen als die Kontrolltiere. Es wurde vermutet, daß dieser Unterschied zwischen den experimentellen Tieren und den Kontrolltieren darauf beruht, daß die Entfernung eines Teils des cerebellären Cortex die Verbindungen zu Strukturen, die bei dem Habituationsprozeß eine Rolle spielen, stört.
    Type of Medium: Electronic Resource
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