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  • 1970-1974  (3)
  • Morphine  (2)
  • Lamina ganglionaris  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of morphine on sleep in the cat (1972)
    Springer
    Psychopharmacology 24 (1972), S. 435-448 
    Details
    ISSN: 1432-2072
    Keywords: Sleep ; Morphine ; Naloxone ; α-Methyltyrosine ; 5-Hydroxy-tryptophan.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of morphine sulfate, 300 μg/kg s.c., on the sleep of cats was studied by electroencephalographic techniques. In contrast to placebo experiments the animals were awake for approximately 6 h after administration of morphine; the return of regular sleep patterns occurred after about 11 h. A rebound increase in rapid eye movement (REM) sleep time and percentage was noted during the 11th through the 17th hour of the study. Sleep following manual sleep deprivation for 10 h showed a rebound increase in REM and non-rapid eye movement (NREM) sleep time. NREM sleep rebound after manual sleep deprivation exceeded that occurring after morphine. The alerting actions of morphine could be blocked by naloxone, 100 μg/kg s.c., for about 90 min. Naloxone alone increased REM sleep time and percentage. Single (84 mg/kg) or multiple (51 mg/kg for 4 injections) doses of dl-α-methyltyrosine i.p. did not block the alerting action or REM sleep rebound caused by morphine. 5-Hydrotryptophan (30 mg/kg) i.p. did not antagonize the alerting action of morphine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00402538
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Morphine dependence in rats with medial forebrain bundle lesions (1973)
    Springer
    Psychopharmacology 30 (1973), S. 343-348 
    Details
    ISSN: 1432-2072
    Keywords: Morphine ; Withdrawal ; Addiction ; Dependence ; Medial Forebrain Bundle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Rats with posterior medial forebrain bundle (PMFB) lesions and control rats were administered morphine chronically for 4 or 5 days via implanted subcutaneous silicone reservoirs. Following cessation of morphine administration after five days, PMFB rats showed less withdrawal-induced weight loss than control rats. Other PMFB and control rats were subjected to forced drinking of morphine solution for 9 days. PMFB rats consumed the morphine solution much more readliy than control rats, whereas intake of a quinine solution was similar in two other PMFB and control groups. These results suggest that the addictive and dependence properties of morphine may have separate mechanisms and based on previously reported neurochemical effects of PMFB lesions, that biogenic amines may be differentially involved in such mechanisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00429193
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Scanning electron microscopy of the insect compound eye (1972)
    Springer
    Cell & tissue research 126 (1972), S. 437-445 
    Details
    ISSN: 1432-0878
    Keywords: Eye ; Sarcophaga bullata ; Ommatidia ; Lamina ganglionaris ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary External and internal surfaces of the compound eye of the flesh fly, Sarcophaga bullata, were examined with a scanning electron microscope. A low patterned corneal nippleridge array and sparse setiform interfacetal hairs were observed on the corneal lens surface. Particular cleavage planes revealed outlines of the Semper Cells, their nuclei and distal terminations of photoreceptor cells. The latter, with their axonal processes, were visualized and described. These axons were noted traversing the external chiasma and entering the lamina ganglionaris where suggestions of synaptic contact were pointed out. The present descriptions were correlated with those taken from literature of the transmission electron microscope.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306904
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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