ISSN:
1432-0878
Keywords:
Synaptogenesis
;
Spinal cord
;
Chick embryo
;
Coated vesicles
;
Ultrastructure
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Synaptogenesis was studied in 3, 4, 5 and 8 day embryos. A small number of synapses were located in the marginal zone near the motor region in 3–4 day embryos. At 5 days the number of synapses increased and synapses were also found within the motor region. At 8 days there was a large increase in the total number of synapses and most were found within the motor region. At this stage, for the first time, many knobs contained flattened synaptic vesicles. Synapses on the perikarya were rarely but occasionally observed both at the 5 and 8 day stages. A few synapses were located in the marginal zone near dorsal root entry at the 5 day stage and the number increased by the 8 day stage. Although this sequence of synaptic development resembles that found in the monkey fetus, differences in behavioral development between these two species indicate that descriptive relationships between synaptic and behavioral development must be made cautiously. Furthermore, evidence is presented which indicates that the junctional specialization is the first sign of a developing synapse and that coated vesicles, possibly derived from the Golgi apparatus, which are fused to the neural plasmalemma may be related to the initial formation of the junctional specialization.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00572291
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