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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 95 (1973), S. 1657-1659 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 27 (1974), S. 201-213 
    ISSN: 1432-0533
    Keywords: Infantile Neuroaxonal Dystrophy ; Spheroids ; Perikaryon ; Electron Microscopy ; Membranous Profiles ; Dense Bodies ; Protein Syntheses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Electron microscopic findings of a cortical biopsy from a four-year-old child suffering from muscular weakness and psychomotor retardation are presented. Morphological evidence obtained in this study suggests a unique pathogenetic mechanism underlying INAD. The spheroids appear to be caused by an accumulation of a macromolecular substance synthesized in the neuron and transported to the nerve endings. The abnormal substance initially takes the form of an amorphous material, it eventually aggregates into highly characteristic angulated membranous profiles. The selective involvement of the nerve endings, synapses and motor end plates in this disease suggests a derangement of the metabolic pathway in the synthesis or packaging of the neurotransmitters or their receptors.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 23 (1973), S. 133-140 
    ISSN: 1432-0533
    Keywords: Metachromatic Leukodystrophy ; Neuronal Inclusions ; Laminated Bodies ; Mucopolysaecharides ; Electron Microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ultrastructural findings of the metachromatic granules in the anterior horn cells of the spinal cord in a case of metachromatic leukodystrophy are presented. The typical neuronal inclusions are concentrically laminated bodies of approximately 1 μ. In addition various morphological variations of the abnormal inclusions are seen side by side in the same neuron and give the impression that the highly organized laminated bodies are formed as a result of progressive deposition of membranous material upon a nidas which is initially amorphous, which then becomes granular, fibrillar or horizontally striped and finally multilaminated. Material capable of binding colloidal iron particles is demonstrated in these inclusions, and suggests the presence of mucopolysaccharides.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 16 (1970), S. 262-265 
    ISSN: 1432-0533
    Keywords: Remyelination ; Landry-Guillain-Barré-Syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die ultrastrukturelle untersuchung der peripheren Nerven eines Falles von Landry-Guillain-Barré Syndrom, der während einer kurzen Erholungsphase starb, ergibt charakteristische Befunde, die als regenerative Veränderung gedeutet werden. Um jedes Axon sieht man geschlossene Lagen von Vesikeln und Tubuli; das Verschmelzen dieser Vesikeln scheint von der Bildung der Myelinlamellen gefolgt zu werden. Es drängt sich die Annahme auf, daß die Vesikeln vom endoplasmischen Reticulum der Axone gebildet werden.
    Notes: Summary Ultrastructural study of peripheral nerves in a case of Landry-Guillain-Barré syndrome dying during early recovery phase reveals characteristic findings which are inter preted as being regenerative changes. Layers of compact vesicles and tubules are seen around each axon and coalescence of these vesicles appears to be followed by formation of myelin lamella. There is suggestive evidence that the vesicles may be produced by the endoplasmic reticulum of the axon.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 10 (1974), S. 201-222 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Résumé La relation de propagation des fissures de fatigue peut être obtenue à partir de trois hypothèses: déformations plastiques de faible étendue, homogénéité du matériau, et relative indifférence à l'épaisseur de la tole des contraintes et déformations à la pointe de la fissure, f(R) est une constante à rapport des contraintes R fixé. On a étudié les effets de l'épaisseur de la tole et du rapport des contraintes sur la déformation à l'extrémité de la fissure et sur la propagation de la fissure de fatigue, dans le cas de l'alliage d'aluminium 2024-T351. On constate que des valeurs élevées de ΔK appliquées à des échantillons minces produisent une striction aux extrémités de la fissure. Cette striction est plus prononcée aux valeurs élevées de R, et produit une déformation maximum εmax élevée au voisinage de la pointe de la fissure, ainsi qu'une vitesse de propagation élevée. Pour éviter les effets perturbateurs de la striction aux extrémités d'une fissure, il conviendrait d'utiliser des éprouvettes dont l'épaisseur soit plus forte que 2,5 (ΔK/σY(c))2.
    Abstract: Zusammenfassung Die Gleichung da/dN = f(R)ΔK2 für Müdigkeitsrißausdehnung kann mittels drei Hypothesen zugestellt werden: kleine plastische Verformungen, Homogenität des Materials, und daß die Spannungen und Verformungen an der Rißspitze nicht stark von der Plattendicke beeinflußt werden. f(R) ist eine Konstante für ein gegebenes Spannungs-verhältnis R. Man untersucht den Einfluß der Plattendicke und des Spannungsverhältnisses auf die Verformungen der Spitze des Risses und der Müdigkeitsrißausdehnung in einer Aluminiumlegierung 2024-T351. Ein hoher ΔK Wert in einer dünnen Probe führt zu Striktion an der Rißspitze. Die Striktion ist stärker für hohe Spannungsverhältnisse. Die Striktion verursacht eine große Höchstspannung E max in der Nähe einer Rißspitze und einen schnellen Rißwachstumsgrad. Zur Vermeidung der Einflüsse der Rißspitzestriktion soll man Platten benutzen die dicker sind als 2,5 (ΔK/σY(c))2.
    Notes: Abstract The fatigue crack propagation relation da/dN = f(R)ΔK2 can be derived with three assumptions: small scale yielding, material homogeneity and that crack tip stresses and strains are not strongly affected by plate thickness. f(R) is a constant at a given stress ratio, R. The effects of plate thickness and stress ratio on crack tip deformation and fatigue crack growth in 2024-T351 aluminum alloy were studied. High ΔK level in a thin specimen causes crack tip necking. Necking is more pronounced at high stress ratio. Necking causes high maximum strain near a crack tip, εmax, and fast crack growth rate. In order to avoid the effects of crack tip necking, plates thicker than 2.5 (ΔK/σY(c))2 should be used.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 143 (1974), S. 337-347 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Scanning electron microscopy revealed spores of Nosema apis and Thelohania fibrata to be egg-shaped, but only the mature spore of T. fibrata was shown to possess a horseshoe-like concavity at the posterior pole. Freezeetched preparations indicated that this concavity was due to a thin area of the spore coat. Freeze-etching studies also show spores of N. apis do possess an umbrella-shaped polaroplast, and a polar filament which is arranged in a double layer with over 30 coils. The spore of T. fibrata contains a pear-shaped arrangement of the polaroplast membrane, and a polar filament arranged in a single layer of 22 coils.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 7 (1971), S. 487-490 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 9 (1973), S. 255-266 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Résumé Les déformations locales au voisinage de l'extrémité d'une entaille ont été étudiées dans le cas d'éprouvettes fissurées sollicitées au delà de la limite élastique. Les COD et les dilatations près de l'entaille on été mesurées par la technique du Moiré. On a également mesuré les dilatations d'ensemble dans la section fissurée, et l'on a trouvé que ces trois quantités sont liées l'une à l'autre par des relations linéaires. Les distributions des déformations en surface près d'une fissure sont influencées par la striction locale à l'extrémité de la fissure, qui est sous la dépendence de l'épaisseur de la tôle.
    Abstract: Zusammenfassung Die lokalen Verformungen in der Umgebung der Spitze eines Kerbes wurden für den Fall einer gerissenen, und Beanspruchungen oberhalb der Elastizitätsgrenze ausgesetzten Probe, untersucht. Die COD und die Dehnungen in der Umgebung des Kerbes wurden nach dem Moiré-Verfahren bestimmt. Außerdem wurden die Gesamtdehnungen in der gerissenen Ebene gemessen. Es ergab sich ein linearer Zusammenhang zwischen diesen drei Größen. Die Verteilung der Verformungen an der Oberfläche in der Nähe eines Risses werden durch die lokale Einschnürung and der Rißspitze beinflußt. Letztere hängt ihrerseits von der Dicke des Bleches ab.
    Notes: Abstract The local deformation near a crack tip were investigated when a cracked specimen was stressed beyond general yielding. Crack opening displacements, and near tip strains were measured by the moire technique. The gross elongation in the cracked-section was also measured. These three quantities were found to be linearly related to each other. Surface strain distributions near a crack are influenced by the local necking at the crack tip, which is controlled by the plate thickness.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 8 (1972), S. 223-226 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    International journal of fracture 8 (1972), S. 223-226 
    ISSN: 1573-2673
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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