ISSN:
1432-0428
Keywords:
glucose anomers
;
insulin release
;
glucagon
;
mutarotation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The precise mechanism of insulin release is unknown, though the presence of a beta cell surface receptor has been postulated. As D-glucose exists in at least two anomeric forms, α andβ, these were employed to study insulin release in three animal models. After rapid dissolution, each anomer was rapidly injected into intact rats, dogs, and a rat pancreatic perfusion system. There was a trend toward greater insulin secretion and greater suppression of glucagon by the α. anomer.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01219543
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