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  • 1
    Electronic Resource
    Electronic Resource
    THE ROLE OF NERVE GROWTH FACTOR IN THE RAMIFICATION OF SYMPATHETIC NERVE FIBRES INTO THE RAT IRIS IN ORGAN CULTURE (1972)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 19 (1972), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Small amounts of nerve growth factor (NGF) were present in the superior cervical ganglion and the iris of the rat. The observations that NGF content in each of the tissues was depleted during organ culture and that more NGF appeared in the media than was originally present in the tissues indicated that synthesis or activation of NGF had occurred in organ culture. Antibody to NGF or the depletion of endogenous NGF retarded growth of new sympathetic axons into irides in organ culture. Exogenously added NGF appeared to enhance the initiation of axonal sprouting and the rate of the ramification of nerve fibres.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1972.tb05112.x
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  • 2
    Electronic Resource
    Electronic Resource
    Induction of dopamine-β-hydroxylase in rat superior cervical ganglia in organ culture (1972)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 19 (1972), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1972.tb01410.x
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  • 3
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    DISCUSSANTS (1974)
    Waltham, Mass. : Periodicals Archive Online (PAO)
    American Jewish History. 63:4 (1974:June) 375 
    Details
    ISSN: 0164-0178
    Topics: History , Theology and Religious Studies
    Notes: CONTEMPORARY JEWISH CIVILIZATION ON THE AMERICAN CAMPUS: RESEARCH AND TEACHING
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:3033-1974-063-04-000010
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  • 4
    Electronic Resource
    Electronic Resource
    Heterologous Reinnervation of the Iris from Sympathetic Ganglia in Organ Culture (1972)
    [s.l.] : Nature Publishing Group
    Nature 239 (1972), S. 466-468 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To study the selectivity of the process of reinnervation, heterologous matchings of iris and ganglia in culture were examined. We report here cross-species ramification of neuronal fibres from ganglia of the rat, mouse and guinea-pig into heterologous irises. Fig. 1 Rat iris cultured with a mouse ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/239466a0
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  • 5
    Electronic Resource
    Electronic Resource
    The role of the vagus nerve in cardiac adaptation to exercise (1971)
    Springer
    Pflügers Archiv 325 (1971), S. 113-124 
    Details
    ISSN: 1432-2013
    Keywords: Vagus Nerve ; Cardiac Adaptation ; Cardiac Denervation ; Exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ten dogs were subjected to bilateral removal of thoracic sympathetic chains so as sympathetically to denervate the heart while leaving vagal control intact (so-called Vagal Dogs). Their cardiac output was then estimated at different levels of exercise. The estimation was repeated on eight of these same animals about a year later with almost identical results. Comparing these results with cardiac exercise outputs of seven normal dogs, it emerges that possession of the vagus alone allows normal cardiac response during exercise. Surprisingly, cutting both vagi in these vagal dogs resulted in practically no immediate deterioration of their cardiac response to exercise. These recently vagotomized animals were then contrasted with a group of eight dogs whose hearts had been completely denervated some months previously. The latter had relatively poor cardiac adaptation to exercise. It was concluded that in the sympathectomized dogs even the recent possession of the vagus confers almost full power of cardiac adaptation to exercise. It is suggested that the recent possession of the vagus has trophic influence on the heart enabling it to retain mitochondria essential to normal function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00587002
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  • 6
    Electronic Resource
    Electronic Resource
    Mechanism of conductivity of bimolecular lipid membranes in the presence of tetrachlorotrifluoromethylbenzimidazole (1974)
    Springer
    The journal of membrane biology 18 (1974), S. 243-261 
    Details
    ISSN: 1432-1424
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The purpose of the work presented in this paper was to determine experimentally the actual mechanism of lipid bilayer conductivity in the presence of tetrachlorotrifluoromethylbenzimidazole (TTFB). The capacitance and conductance of lipid bilayers were measured with a current-clamp method, as a function of equal TTFB concentrations (10−7 to 5×10−5 m) in the two aqueous phases. The voltage across the membrane was measured as a function of time during rectangular current pulses. If the hydrogen buffer capacity of the solution is low, the voltage response to long current pulses has two components. The slow component is due to hydrogen ion concentration changes in the unstirred layers. This component disappears if the buffer capacity is made high enough. Membrane capacitance and conductance can be determined from the fast component of the voltage response. The conductance increases with the square of TTFB concentration (pH 2 to 7) and the capacitance is 0.4 μF/cm2 for the range of concentration used. If solutions of low buffer capacity are used, shifts of hydrogen ion concentrations near the membrane give rise to a complicated dependence of the membrane potential on pH given a unit pH difference between the two aqueous solutions (protonic potential). This dependence can be explained if the membrane permeability for neutral uncoupler molecules (TH) is high enough. The membrane permeability coefficient is determined:P TH=10 cm/sec. In other experiments the dependence of short-circuit current on pH difference between the two solutions was also measured, with the pH value on one side fixed in a given experiment. These complicated nonmonotonic dependences can be described using a mathematical equation with only two parameters: (1) the dissociation constant of TTFB in water (pK=5.2), and (2) the proportionality factor between short-circuit current and TTFB concentration squared. These data can be formally interpreted to mean that the membrane is permeable only to T2H− and TH, where T is TTFB anion and H is hydrogen ion. However, this model does not explain the high current values obtained because of the limited rate constant of T2H− formation in aqueous solution. An alternative model is proposed. It is shown that the T2H− is not formed in aqueous phase but rather within the membrane. The T2H− can be the intramembrane charge carrier if its life-time is long enough. If the average life-time is short, current might be carried through the membrane by proton exchange between TH and T−, when they collide. This mechanism could also account for the action of uncouplers of oxidative phosphorylation other than TTFB.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01870115
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  • 7
    Electronic Resource
    Electronic Resource
    Further genetic mapping of the phoA-phoR region for alkaline phosphatase synthesis in Escherichia coli K12 (1970)
    Springer
    Molecular genetics and genomics 109 (1970), S. 18-26 
    Details
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Genetic mapping of the E. coli chromosomal region carrying the structural gene (phoA) and the regulatory gene (phoR) for alkaline phosphatase synthesis was carried out by conjugation. Recombinant colonies were selected and the segregation frequency of outside markers was determined. The genetic order lac phoA proC phoR tsx lon is proposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00334043
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  • 8
    Electronic Resource
    Electronic Resource
    Raman spectrum of the addition compound of uranium and phosphorus pentachlorides (UCl5,·PCl5) and its structure (1974)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 2 (1974), S. 623-628 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The Raman spectrum of the addition compound of PCl5 · UCl5 was recorded. In all, seven major lines were observed. The results were interpreted as supporting the ionic structure of PCl4+ UCl6-, the cation having a Td symmetry and the anion an Oh symmetry.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250020609
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