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  • 1970-1974  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    A LIGHT-SCATTERING TECHNIQUE FOR THE STUDY OF THE PERMEABILITY OF RAT BRAIN SYNAPTOSOMES IN VITRO (1970)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 17 (1970), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— (1) Swelling of synaptosomes was measured spectrophotometrically by recording changes in extinction at 520 nm.(2) Synaptosomes behaved as osmometers in NaCl solutions. When the tonicity of the medium was changed, synaptosome volume changed in accordance with Boyle and van't Hoff's Law. These changes were reversed on restoring the tonicity of the medium.(3) The rate at which a solute entered the synaptosome was determined from the rate of swelling in the presence of that solute. Permeability of synaptosomes to non-electrolytes was in the order glucose ≪ glycerol 〈 thiourea = formamide 〈 propylene glycol = dimethylsulphoxide.(4) Synaptosomes were freely permeable to ammonium and acetate ions and impermeable to Ca2+, Mg2+, PO42−, SO42− and oxalate ions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1970.tb00535.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    THE PERMEABILITY OF PINCHED-OFF NERVE ENDINGS TO SODIUM, POTASSIUM AND CHLORIDE AND THE EFFECTS OF GRAMICIDIN (1971)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 18 (1971), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— 〈list xml:id="l1" style="custom"〉1The passive permeability of synaptosomes to ions was measured by a light-scattering technique. Synaptosomes were freely permeable to acetate, HCO3_, SCN−and NH4+ and were impermeable to choline and SO42-.2Gramicidin D selectively increased the permeability of synaptosomes to Na+ and K+ ions.3The relative permeabilities of Na+, K+ and Cl−, measured in the presence of a number of more permeant counter-ions, was in the ratio 1:19:12. These values are discussed in terms of the source of the resting potential.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1971.tb12038.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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