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  • 1
    ISSN: 1432-2013
    Keywords: Inspiratory Gas Exchange ; Measurement of O2, CO2, and He in the Alveolar Air ; Rapid Measuring Platinum Electrode ; $$\dot V_{A^ - } , \dot Q_ - $$ andD L -Distribution Curves ; AαD Components ; Inspiratorischer Gaswechsel ; Alveoläre O2-, CO2-, He-Registrierung ; Schnellregistrierende Platinelektrode ; $$\dot V_{A^ - } , \dot Q_ - $$ ,D L -Verteilungskurven ; AαD-Anteile
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird der Untersuchungsgang und die Auswertung für das Verfahren der gleichzeitigen Verteilungsanalyse von Ventilation, Lungendurchblutung und O2-Diffusionskapazität beschrieben. Die Versuchsperson atmet dabei im offenen spirometrischen System ein Gasgemisch (12 Vol-% O2, 30 Vol-% He und 58 Vol-% N2), das plötzlich durch ein anderes Inspirationsgemisch (16 Vol-% O2, 4,8 Vol-% CO2 und 79,2 Vol-% N2) ersetzt wird. In der Phase der nachfolgenden alveolären Ein- bzw. Auswaschprozesse werden die endexspiratorischen Konzentrationen fortlaufend verfolgt. Die Analyse des Sauerstoffes erfolgt dabei mit einer schnellregistrierenden Platinelektrode, die des Kohlendioxyds mit einem Ultrarotabsorptionsschreiber und die Heliumbestimmung mit einem trägheitslosen Katapherometer. Gleichzeitig wird das Atemzugvolumen mit Hilfe eines integrierenden Pneumotachographen registriert. Das Auswerteverfahren ist so angelegt, daß zunächst die relativen Größen von Ventilation, Perfusion und Diffusionskapazität in vier funktionell in sich einheitlichen Lungenkompartimenten ermittelt und daraus dann die Anteile der alveolär-arteriellen Druckdifferenzen für O2 bzw. CO2 berechnet werden. Der in elf Schritten standardisiert durchzuführende Gang der Auswertung wird anhand eines Beispiels erläutert.
    Notes: Summary The examination and the evaluation procedure of the method of simultaneous distribution analysis of ventilation, lung perfusion, and O2 diffusing capacity are described. The test person breathes, in an open spirometric system, a gas mixture (12 vol-% O2, 30 vol-% He, and 58 vol-% N2), which is suddenly replaced by another inspiration mixture (16 vol-% O2, 4.8 vol-% CO2, and 79.2 vol-% N2). In the subsequent alveolar wash-in and wash-out phase, the endexpiratory concentrations are continually followed. The oxygen is analysed by means of a rapid-measuring platinum electrode, the carbon dioxide by an infra-red absorption recorder, and the helium by an inertialess catharometer. Simultaneously, the tidal volume is registered with the aid of an integrating pneumotachograph. The evaluation process is designed to enable first of all the determination of the relative values of ventilation, perfusion, and diffusing capacity in four functionally uniform lung compartments. After this, the components of the alveolar-arterial pressure differences for O2 and CO2 are calculated. The evaluation process, to be carried out in standardized form, in eleven steps, is explained by means of an example.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 78 (1966), S. 595-596 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The complex dielectric constant of aqueous hemoglobin solution was measured at 9.5 GHz. A microwave technique allowing phase and attenuation settings with an accuracy of 0.3° and 0.03 db was used. The shift of the relaxation wavelength and the hydration values of horse hemoglobin were determined for native and lyophilized hemoglobin solution and erythrocytes suspensions as well. The isotope effect of light and heavy water on these parameters was detected. The influence of buffers was studied. Relative measurements, with the sensitivity increased by a factor of 20, were made with alternating oxygenated and deoxygenated human hemoglobin solutions. The oxygenation of hemoglobin was found to leave the hydrated molecule volume invariant within ±250 Å3, while a shift of the relaxation wavelength of 0.0025 ± 0.0015 cm occurs for a hemoglobin concentration of 107 g/l. The results are discussed in terms of the structure and function interrelationship of hemoglobin and the current picture of water structure.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Dielectric dispersion measurements with aqueous solutions of hemoglobin and myoglobin have been performed in the frequency range from 100 kcps to 15 Mcps. The influence of preparation, particle size, and solvent conditions was studied. The results are analyzed in terms of an orientational polarization mechanism.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 5 (1966), S. 586-586 
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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